Projects per year
Personal profile
Personal profile
Dr. Hu, a Neuroscientist, joined Houston Methodist in July 2022. He earned his M.D. and Ph.D. degrees from the University of South China. Dr. Hu completed his postdoctoral training under the mentorship of Dr. Jun Li at Vanderbilt University and was appointed as a Research Instructor at Vanderbilt University in 2017. He joined the Department of Neurology at Wayne State University to be an Assistant Professor in 2018 until his relocation to Houston Methodist in 2022. His research has been supported by the NIH funds.
Research interests
Dr. Hu concentrates on studying the pathogenesis of demyelination in peripheral nerve diseases. Demyelination is a common pathology in various peripheral neuropathies which collectively are highly prevalent. In contrast to axonal degeneration in peripheral neuropathies that are not responsive to treatments, demyelination often improves with treatments. Therefore, it is important to understand the underlying mechanisms leading to demyelination. Dr. Hu's team is focused on the altered intercellular interactions among Schwann cells, axons, and macrophages in demyelinating diseases, and aims to determine how these molecular changes trigger segmental demyelination. The goal of Dr. Hu’s research is to identify key molecular targets that can be manipulated to halt or rescue the demyelination process.
Education/Academic qualification
Pathology, PhD, University of South China
Sep 1 2008 → Jun 1 2011
Award Date: Jun 1 2011
Pathology, MS, University of South China
Sep 1 2004 → Jun 1 2007
Award Date: Jun 1 2007
Medicine, BMS, University of South China
Sep 1 1998 → Jun 1 2003
Award Date: Jun 1 2003
External positions
Assistant Professor of Physiology in Neurology, Weill Cornell Medical College
Jul 1 2024 → …
Research Area Keywords
- Neurosciences
Free-text keywords
- Demyelinating diseases
- Inherited peripheral nerve diseases
- Myelin biology
- Remyelination
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Collaborations and top research areas from the last five years
Projects
- 1 Active
Research output
- 15 Article
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PAK2 is Necessary for Myelination in the Peripheral Nerve System
Hu, B., Moiseev, D., Schena, I., Faezov, B., Dunbrack, R., Chernoff, J. & Li, J., Dec 11 2023, (E-pub ahead of print) In: Brain.Research output: Contribution to journal › Article › peer-review
Open Access -
C698R mutation in Lrsam1 gene impairs nerve regeneration in a CMT2P mouse model
Moiseev, D., Wazir, Z., Liu, D., Li, J. & Hu, B., Jul 16 2022, In: Scientific Reports. 12, 1, p. 12160 10 p., 12160.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Leucine zipper transcription factor-like 1 (LZTFL1), an intraflagellar transporter protein 27 (IFT27) associated protein, is required for normal sperm function and male fertility
Huang, Q., Li, W., Zhou, Q., Awasthi, P., Cazin, C., Yap, Y., Mladenovic-Lucas, L., Hu, B., Jeyasuria, P., Zhang, L., Granneman, J. G., Hess, R. A., Ray, P. F., Kherraf, Z. E., Natarajan, V. & Zhang, Z., Sep 2021, In: Developmental Biology. 477, p. 164-176 13 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Abnormal fertility, acrosome formation, IFT20 expression and localization in conditional Gmap210 knockout mice
Wang, Z., Shi, Y., Ma, S., Huang, Q., Yap, Y. T., Shi, L., Zhang, S., Zhou, T., Li, W., Hu, B., Zhang, L., Krawetz, S. A., Pazour, G. J., Hess, R. A. & Zhang, Z., 2020, In: American Journal of Physiology - Cell Physiology. 318, 1, p. C174-C190Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Demyelination in hereditary sensory neuropathy type-1C
Saba, S., Chen, Y., Maddipati, K. R., Hackett, M., Hu, B. & Li, J., Sep 1 2020, In: Annals of Clinical and Translational Neurology. 7, 9, p. 1502-1512 11 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations
Prizes
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Travel Award for147th Annual Meeting of the American Neurological Association
Hu, B. (Recipient), Jul 5 2022
Prize: Prize (including medals and awards)