Projects per year
Personal profile
Personal profile
Dr. Cristini is a leading expert and researcher in the fields of mathematical and computational biology, applied and computational mathematics, physical oncology, complex fluids and microfluidics, multidisciplinary (bio)materials science, and systems biology and medicine.
He was included in the 2014 ISI Highly-Cited Researchers in Mathematics, a total of less than one hundred mathematicians worldwide named “most influential scientific minds.” He served as editor for Cancer Research and several biomedical journals including NeuroImage and PloS Computational Biology. He has published two book monographs with Cambridge University Press in 2010 and with CRC Press in 2017, and over 90 peer-reviewed journal articles.
Dr. Cristini was the first recipient of the “Andreas Acrivos Dissertation Award in Fluid Dynamics” by the American Physical Society in 2000. His 2005 paper in the Bulletin of Mathematical Biology was in the top 0.1% of citations in the field of Mathematics and has been designated as a “New Hot Paper in the field of Mathematics” by the Institute for Scientific Information (ISI) Web of Knowledge; two articles have been featured in the Cancer Research Highlights of the American Association for Cancer Research. His research has been highly recognized internationally and by the media and several science museums in the US, and has been supported by the Cullen Trust for Health Care, the National Science Foundation, the National Institutes of Health, the Department of Defense, the States of California, Texas and New Mexico among the others.
For more than 15 years, Dr. Cristini has continually served in PI roles on several NSF, NIH, and DoD grants focused on the development of predictive multi-scale patient-specific computational models of tumor growth and mechanistic mathematical models of tumor response to chemo/immunotherapy, targeted therapy, and nano-therapeutics, most notably as part of multinstitutional grants including two NSF and joint NSF/NIGMS grants (funded in September 2017 and 2013, respectively), two R01s beginning in April and July 2018, two U01 NCI grants on pancreatic and gynecological cancers (funded in August 2015 and July 2017, respectively), two NCI Physical Sciences in Oncology Centers (PS-OC), one NCI Center for Excellence in Cancer Nanotechnology (CCNE), of which he served as the overall PI in 2015-2016, one NCI Integrative Cancer Biology Program (ICBP) center grant, and one NIGMS P50 grant in systems biology.
Dr. Cristini has developed and taught novel courses in Computational and Precision Biomedicine, and has mentored and trained graduate students, postdocs, and junior faculty, including the NIGMS Spatio-Temporal Modeling Center (STMC UNM) and the NIGMS-IRACDA Academic Science Education and Research Training (ASERT) program mentees.
External positions
Professor of Population Health Sciences, Weill Cornell Medical College
Oct 1 2021 → …
Research Area Keywords
- Cancer
- Nanomedicine
- Neurosciences
- Immunobiology & Inflammation
- Systems Medicine & Bioinformatics
- Precision Medicine
- Regenerative Medicine
- Clinical Translation & Trials
Free-text keywords
- Mathematical modeling
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Collaborations and top research areas from the last five years
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Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer
Wang, Z. (PI) & Cristini, V. (Key Personnel)
3/4/21 → 2/28/26
Project: Federal Funding Agencies
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The University of Texas M.D. Anderson Cancer Center SPORE in Hepatocellular Carcinoma
Cristini, V. (PI)
9/1/20 → 8/31/24
Project: Federal Funding Agencies
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Imaging and Molecular correlates of progression in cystic neoplasms of the pancreas
Cristini, V. (PI) & Wang, Z. (Key Personnel)
9/1/18 → 8/31/21
Project: Federal Funding Agencies
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miR-155 targeted therapeutics for precision medicine in lung cancer
Cristini, V. (PI) & Wang, Z. (Key Personnel)
8/3/18 → 7/31/23
Project: Federal Funding Agencies
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A Targeted Nanomedicine Prototype Against Enzalutamide-resistant Prostate Cancer
Cristini, V. (PI) & Wang, Z. (Key Personnel)
8/1/18 → 7/31/23
Project: Federal Funding Agencies
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Clinical Validation of Mathematically Derived Early Tumor Dynamics for Solid Tumors in Response to Durvalumab
Li, Q., Cristini, V., Gupta, A., Achour, I., Barrett, J. C. & Koay, E. J., Jul 2024, In: JCO clinical cancer informatics. 8, p. e2300254 00074.Research output: Contribution to journal › Article › peer-review
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Gradient-induced instability in tumour spheroids unveils the impact of microenvironmental nutrient changes
Ascione, F., Ferraro, R., Dogra, P., Cristini, V., Guido, S. & Caserta, S., Dec 2024, In: Scientific Reports. 14, 1, 20837.Research output: Contribution to journal › Article › peer-review
Open Access -
Hybridizing mechanistic modeling and deep learning for personalized survival prediction after immune checkpoint inhibitor immunotherapy
Butner, J. D., Dogra, P., Chung, C., Koay, E. J., Welsh, J. W., Hong, D. S., Cristini, V. & Wang, Z., Aug 14 2024, In: npj Systems Biology and Applications. 10, 1, p. 88 88.Research output: Contribution to journal › Article › peer-review
Open Access -
A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection
Dogra, P., Schiavone, C., Wang, Z., Ruiz-Ramírez, J., Caserta, S., Staquicini, D. I., Markosian, C., Wang, J., Sostman, H. D., Pasqualini, R., Arap, W. & Cristini, V., Jul 10 2023, In: JCI insight. 8, 13, e169860.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands
Staquicini, D. I., Cardó-Vila, M., Rotolo, J. A., Staquicini, F. I., Tang, F. H. F., Smith, T. L., Ganju, A., Schiavone, C., Dogra, P., Wang, Z., Cristini, V., Giordano, R. J., Ozawa, M. G., Driessen, W. H. P., Proneth, B., Souza, G. R., Brinker, L. M., Noureddine, A., Snider, A. J. & Canals, D. & 9 others, , Aug 22 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 34, p. e2220269120 e2220269120.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Prizes
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Award for Excellence in Peer-Reviewed Publication
Cristini, V. (Recipient) & Wang, Z. (Recipient), Oct 31 2018
Prize: Prize (including medals and awards)
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Career Cornerstone Award- Dr. Wang
Cristini, V. (Recipient), 2021
Prize: Prize (including medals and awards)
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President’s Award for Excellence in Peer-Reviewed Publication
Butner, J. (Recipient), Wang, Z. (Recipient) & Cristini, V. (Recipient), Jan 4 2021
Prize: Prize (including medals and awards)
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President’s Award for Excellence in Peer-Reviewed Publication
Cristini, V. (Recipient), 2021
Prize: Prize (including medals and awards)
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The Cockrell Foundation Professorship Award
Cristini, V. (Recipient), 2021
Prize: Prize (including medals and awards)