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  BI 1425-0003 - Phase IIa - Crohn's Study - A Phase IIa, randomised, double-blind, placebo-controlled trial to evaluate the safety, efficacy, pharmacokinetics and pharmacodynamics of BI 706321 orally administered for 12 weeks in patients with Crohn`s Disease (CD) receiving ustekinumab induction treatment

  Abraham, B. P. & Glassner, K.

  10/3/22 → …

  Project: Clinical Trial

• A Multi-Center, Real-World Evidence Registry to Assess Outcomes for the Long-Term Impact of Catheter Ablation for Atrial Fibrillation: DYNAMIC AF Registry

  9/30/22 → …

  Project: Clinical Trial

• A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Clinical Trial to Evaluate the Tolerability, Safety, and Efficacy of PRAX-944 in the Treatment of Adults with Essential Tremor

  Waln, O. & Ondo, W. G.

  9/28/22 → …

  Project: Clinical Trial

• Safety and Effectiveness Study of the Zenflow Spring System - A Minimally Invasive Treatment for LUTS Associated With BPH

  Gonzalez, R. & Starke, N. R.

  9/27/22 → …

  Project: Clinical Trial

• Malleable Treatment - the Tactra Erectile Restoration Study (It MATTERS)

  Starke, N. R.

  9/23/22 → …

  Project: Clinical Trial

• Relationship of the Human Astrocyte Matrisome with Synaptic Networks

  Krencik, R. C.

  9/23/22 → 7/31/27

  Project: Federal Funding Agencies

• A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-322)

  Shah, S., Ganguly, S., Petkova, J., Pingali, S. R. & Rice, L.

  9/21/22 → …

  Project: Clinical Trial

• A randomized, double-blind, phase III study comparing NIS793 in combination with gemcitabine and nab-paclitaxel versus placebo combined with gemcitabine and nabpaclitaxel for first line treatment of metastatic pancreatic ductal adenocarcinoma (mPDAC)

  Abdelrahim, M., Heyne, K. & Singh, M.

  9/20/22 → …

  Project: Clinical Trial

• Validation of a novel 3D culture platform for TNBC treatment selection

  Yun, K.

  9/20/22 → 8/31/27

  Project: Federal Funding Agencies

• Cephea Mitral Valve System for Treatment of MR EFS Abbott

  Goel, S., Faza, N., Kleiman, N., Little, S. H., Reardon, M. J. & Yousefzai, R.

  9/19/22 → …

  Project: Clinical Trial

• LEAFLEX EFS for Severe Aortic Stenosis Pi-Cardia A Prospective, Multicenter, Non-Randomized, Single-Arm, Open-Label Clinical Study to Demonstrate the Safety and Performance of the Leaflex Performer

  Goel, S., Faza, N., Kleiman, N., Little, S. H. & Reardon, M. J.

  9/15/22 → …

  Project: Clinical Trial

• Eradication of Escaped Variant Tumor Cells for Cancer Immunotherapy

  Lu, Y.

  9/15/22 → 8/31/26

  Project: Federal Funding Agencies

• Vascularized NICHE with local immunosuppression for cell replacement for Type 1 diabetes

  Grattoni, A.

  9/12/22 → 5/31/27

  Project: Federal Funding Agencies

• Type 1 Hydrolyzed Collagen (T1HC) * impact on the reduction of groin wound complications in vascular surgery

  Rahimi, M., Le, L., Lumsden, A. B., Peden, E. K. & Roy, T.

  9/2/22 → …

  Project: Clinical Trial

• Virtual Reality-Based Cognitive Intervention For The Prevention of Delirium & Cognitive Impairment In Geriatric Surgical Patients

  Faisal, H.

  9/1/22 → 8/31/24

  Project: Federal Funding Agencies

• Novel Targeted Therapeutics for Breast Cancer

  Ozpolat, B.

  9/1/22 → 6/30/25

  Project: Federal Funding Agencies

• RESONANCE Registry of the Natural History of Recurrent PeriCarditis (Kiniksa)

  Shah, D. J.

  9/1/22 → …

  Project: Clinical Trial

• Multilevel Intervention Strategies to Transform Kidney Care and Improve Pursuit of Transplant in an Integrated Healthcare Delivery System

  Waterman, A. D.

  8/15/22 → 7/31/23

  Project: Federal Funding Agencies

• A Phase IIa randomized, double-blind, placebo-controlled study of the effects of L-serine on Mild Cognitive Impairment (MCI)

  Roman, G. C., Masdeu, J. C. & Pascual, M. B.

  8/11/22 → …

  Project: Clinical Trial

• CY 6031 Phase 3 - To Evaluate CK3773274 in patients with oHCM, LVOT Cytokinetics, Inc.

  Nagueh, S., Buergler, J. & Kurrelmeyer, K. M.

  8/10/22 → …

  Project: Clinical Trial

• HANSA - Kidney Imlifidase-Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx

  Gaber, A. O., Knight, R. J. & Yi, S.

  8/4/22 → …

  Project: Clinical Trial

• AstroCapsules: A Novel Tool to Detect and Modulate the Neurotrauma Microenvironment

  Krencik, R. C.

  8/1/22 → 7/31/24

  Project: Non Profit

• Dynamics of Colonization and Infection by Multidrug-resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

  Arias, C. A.

  8/1/22 → 7/31/25

  Project: Federal Funding Agencies

• Hydroponic Vegetable Gardening_Quality of Life in Cancer PatientsCaregivers_TAMU Grow It Yourself: The Effect of Hydroponic Vegetable Gardening on Improving Quality of Life in Cancer Patients and Their Caregivers

  Bernicker, E. H. & Satkunasivam, R.

  7/28/22 → …

  Project: Clinical Trial

• JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

  Lumsden, A. B., Le, L., Peden, E. K. & Rahimi, M.

  7/27/22 → …

  Project: Clinical Trial

• An Open-label, Multicenter Trial of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of M1774 in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)

  Singh, M., Abdelrahim, M., Bernicker, E. H., Heyne, K., Niravath, P. A. & Zhang, J.

  7/25/22 → …

  Project: Clinical Trial

• A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension (ELEVATE 2)

  Sahay, S. & Safdar, Z.

  7/21/22 → …

  Project: Clinical Trial

• Open label, multi-center, Phase 1b/2 clinical trial to evaluate the safety and efficacy of autologous CAR-BCMA T cells (CT053) in patients with relapsed and/or refractory multiple myeloma

  Ganguly, S., Petkova, J., Pingali, S. R. & Shah, S.

  7/14/22 → …

  Project: Clinical Trial

• Training in Neural Control of organ Degeneration and Regeneration (NeuralCODR)

  Horner, P. J.

  7/1/22 → 6/30/27

  Project: Federal Funding Agencies

• Methods and devices to assist and improve cerebrospinal fluid drainage

  Britz, G. W.

  7/1/22 → 6/30/24

  Project: Federal Funding Agencies

• Investigation of novel local immunomodulating strategies to enhance islet transplantation for T1D

  Grattoni, A.

  7/1/22 → 6/30/24

  Project: Non Profit

• Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetes

  Grattoni, A.

  7/1/22 → 4/30/26

  Project: Federal Funding Agencies

• Targeting Nitric Oxide Synthase (NOS) Pathway in Obesity-Associated Triple Negative Breast Cancer (TNBC)

  7/1/22 → 6/30/23

  Project: Non Profit

• Neuromodulation for enhanced functional integration of alginate encapsulated pre-organized and networked neural stem cell ribbon grafts

  Horner, P. J.

  7/1/22 → 6/30/24

  Project: Non Profit

• Exploring functional complexes and disease networks within human RNAbinding protein interactomes

  Brannan, K. W.

  7/1/22 → 6/30/25

  Project: Federal Funding Agencies

• Role of CstF64 mediated alternative polyadenylation in heart failure

  Amirthalingam Thandavarayan, R.

  7/1/22 → 6/30/25

  Project: Non Profit

• POR and Training Program on Multidrug-Resistant Organisms

  Arias, C. A.

  7/1/22 → 6/30/26

  Project: Federal Funding Agencies

• A Multicenter, Open-label, Phase 2 Basket Study of MK-7684A, a Coformation of Vibostolimab (MK-7684) with Pembrolizumab (MK-3475), With or Without Other Anticancer Therapies in Participants with Selected Solid Tumors

  Zaid, T., Alaniz, A., Singh, M. & Suri, A.

  6/22/22 → …

  Project: Clinical Trial

• Combining Transcutaneous Spinal Stimulation and Exoskeleton Training in the Rehabilitation of Spinal Cord Injury.

  Sayenko, D. & Kaldis, T.

  6/20/22 → …

  Project: Clinical Trial

• A PHASE III, RANDOMIZED, OPEN-LABEL, MULTICENTER STUDY EVALUATING THE EFFICACY AND SAFETY OF ADJUVANT GIREDESTRANT COMPARED WITH PHYSICIAN's CHOICE OF ADJUVANT ENDOCRINE MONOTHERAPY IN PATIENTS WITH ESTROGEN RECEPTOR-?ITIVE, HER2-NEGATIVE

  6/14/22 → 6/13/32

  Project: Non Profit

• A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)

  Chang, J. C.

  6/10/22 → 5/31/27

  Project: Federal Funding Agencies

• Biomarker development in patients with HNPP

  Li, J.

  6/1/22 → 12/31/22

  Project: Federal Funding Agencies

• Supplementary funding for U01NS104326 Clinical Trial Readiness for SCA1 and SCA3 (?READISCA?)

  Ashizawa, T.

  6/1/22 → 12/31/22

  Project: Federal Funding Agencies

• VENOUS: A translational study of enterococcal bacteremia

  Arias, C. A.

  6/1/22 → 5/31/25

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining its contributions to post-transcriptional gene regulation (Same as parent grant)

  Kiss, D. L.

  6/1/22 → 6/30/25

  Project: Federal Funding Agencies

• Linked by Love: An African-American Family Story About Kidney Disease.

  Waterman, A. D.

  6/1/22 → 5/31/23

  Project: Federal Funding Agencies

• Ultra-long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure

  Grattoni, A.

  6/1/22 → 5/31/27

  Project: Federal Funding Agencies

• Imaging for Precision Medicine in Alzheimer's Disease and Related Disorders

  Masdeu, J. C., Appel, S. H., Faridar, A., Fujita, M., Karmonik, C., Nakawah, M. O., Pascual, M. B., Roman, G. C. & Wong, S. T.

  5/25/22 → …

  Project: Clinical Trial

• A Phase IIa randomized, double-blind, placebo-controlled study of the effects of L-serine on Mild Cognitive Impairment (MCI)

  Roman, G. C.

  5/23/22 → 5/22/26

  Project: Non Profit

• CY 6022-Open-Label Study of CK-3773274 for Patients with oHCM Cytokinetics

  Nagueh, S., Buergler, J. & Kurrelmeyer, K. M.

  5/19/22 → …

  Project: Clinical Trial