Acute appendicitis: Efficacy of prophylactic preoperative antibiotics in the reduction of septic morbidity

Marjorie Fine; Ronald W. Busuttil

doi:10.1016/0002-9610(78)90100-9

Acute appendicitis: Efficacy of prophylactic preoperative antibiotics in the reduction of septic morbidity

Marjorie Fine, Ronald W. Busuttil

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The course of 200 patients who recently underwent appendectomy at UCLA for acute appendicitis has been reviewed to determine the efficacy of preoperative systemic antibiotic prophylaxis in reducing septic morbidity after surgery. Among those with nonperforated appendicitis who were given gentamycin and clindamycin preoperatively, a reduction of infection rate from 10.2 to 5.3 per cent was found when compared with patients who received no antibiotics.

Original language	English (US)
Pages (from-to)	210-212
Number of pages	3
Journal	The American Journal of Surgery
Volume	135
Issue number	2
DOIs	https://doi.org/10.1016/0002-9610(78)90100-9
State	Published - Feb 1978

ASJC Scopus subject areas

Surgery

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10.1016/0002-9610(78)90100-9

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title = "Acute appendicitis: Efficacy of prophylactic preoperative antibiotics in the reduction of septic morbidity",

abstract = "The course of 200 patients who recently underwent appendectomy at UCLA for acute appendicitis has been reviewed to determine the efficacy of preoperative systemic antibiotic prophylaxis in reducing septic morbidity after surgery. Among those with nonperforated appendicitis who were given gentamycin and clindamycin preoperatively, a reduction of infection rate from 10.2 to 5.3 per cent was found when compared with patients who received no antibiotics.",

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AB - The course of 200 patients who recently underwent appendectomy at UCLA for acute appendicitis has been reviewed to determine the efficacy of preoperative systemic antibiotic prophylaxis in reducing septic morbidity after surgery. Among those with nonperforated appendicitis who were given gentamycin and clindamycin preoperatively, a reduction of infection rate from 10.2 to 5.3 per cent was found when compared with patients who received no antibiotics.

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Acute appendicitis: Efficacy of prophylactic preoperative antibiotics in the reduction of septic morbidity

Abstract

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