Abstract
Tissue engineering is a promising solution to address articular cartilage pathology. The creation of strategies for functional replacement of diseased cartilage relies heavily on the knowledge of the physiology and development of articular cartilage, especially in terms of the influence of biomechanical forces on the tissue. This review will present the current knowledge of biomechanical structure-function relationships of native articular cartilage, and synthesize this knowledge with strategies to engineer the tissue in vitro.
| Original language | English (US) |
|---|---|
| Title of host publication | Biomechanical Systems Technology |
| Subtitle of host publication | Muscular Skeletal Systems |
| Publisher | World Scientific Publishing Co. |
| Pages | 1-37 |
| Number of pages | 37 |
| ISBN (Electronic) | 9789812771384 |
| ISBN (Print) | 9812707980, 9789812709837 |
| DOIs | |
| State | Published - Jan 1 2009 |
Keywords
- Articular cartilage
- Mechanobiology
- Mechanotransduction
- Tissue engineering
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology
- General Medicine