Clinical neuroprosthetics: Today and tomorrow

Morgan B. Lee; Daniel R. Kramer; Terrance Peng; Michael F. Barbaro; Charles Y. Liu; Spencer Kellis; Brian Lee

doi:10.1016/j.jocn.2019.07.056

Clinical neuroprosthetics: Today and tomorrow

Morgan B. Lee, Daniel R. Kramer, Terrance Peng, Michael F. Barbaro, Charles Y. Liu, Spencer Kellis, Brian Lee

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Implantable neurostimulation devices provide a direct therapeutic link to the nervous system and can be considered brain-computer interfaces (BCI). Under this definition, BCI are not simply science fiction, they are part of existing neurosurgical practice. Clinical BCI are standard of care for historically difficult to treat neurological disorders. These systems target the central and peripheral nervous system and include Vagus Nerve Stimulation, Responsive Neurostimulation, and Deep Brain Stimulation. Recent advances in clinical BCI have focused on creating “closed-loop” systems. These systems rely on biomarker feedback and promise individualized therapy with optimal stimulation delivery and minimal side effects. Success of clinical BCI has paralleled research efforts to create BCI that restore upper extremity motor and sensory function to patients. Efforts to develop closed loop motor/sensory BCI is linked to the successes of today's clinical BCI.

Original language	English (US)
Pages (from-to)	13-19
Number of pages	7
Journal	Journal of Clinical Neuroscience
Volume	68
DOIs	https://doi.org/10.1016/j.jocn.2019.07.056
State	Published - Oct 2019

ASJC Scopus subject areas

Surgery
Neurology
Clinical Neurology
Physiology (medical)

Access to Document

10.1016/j.jocn.2019.07.056

Cite this

@article{210965282d514a47aba80cf107a1913d,

title = "Clinical neuroprosthetics: Today and tomorrow",

abstract = "Implantable neurostimulation devices provide a direct therapeutic link to the nervous system and can be considered brain-computer interfaces (BCI). Under this definition, BCI are not simply science fiction, they are part of existing neurosurgical practice. Clinical BCI are standard of care for historically difficult to treat neurological disorders. These systems target the central and peripheral nervous system and include Vagus Nerve Stimulation, Responsive Neurostimulation, and Deep Brain Stimulation. Recent advances in clinical BCI have focused on creating “closed-loop” systems. These systems rely on biomarker feedback and promise individualized therapy with optimal stimulation delivery and minimal side effects. Success of clinical BCI has paralleled research efforts to create BCI that restore upper extremity motor and sensory function to patients. Efforts to develop closed loop motor/sensory BCI is linked to the successes of today's clinical BCI.",

author = "Lee, {Morgan B.} and Kramer, {Daniel R.} and Terrance Peng and Barbaro, {Michael F.} and Liu, {Charles Y.} and Spencer Kellis and Brian Lee",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

month = oct,

doi = "10.1016/j.jocn.2019.07.056",

language = "English (US)",

volume = "68",

pages = "13--19",

journal = "Journal of Clinical Neuroscience",

issn = "0967-5868",

publisher = "Churchill Livingstone",

}

TY - JOUR

T1 - Clinical neuroprosthetics

T2 - Today and tomorrow

AU - Lee, Morgan B.

AU - Kramer, Daniel R.

AU - Peng, Terrance

AU - Barbaro, Michael F.

AU - Liu, Charles Y.

AU - Kellis, Spencer

AU - Lee, Brian

PY - 2019/10

Y1 - 2019/10

N2 - Implantable neurostimulation devices provide a direct therapeutic link to the nervous system and can be considered brain-computer interfaces (BCI). Under this definition, BCI are not simply science fiction, they are part of existing neurosurgical practice. Clinical BCI are standard of care for historically difficult to treat neurological disorders. These systems target the central and peripheral nervous system and include Vagus Nerve Stimulation, Responsive Neurostimulation, and Deep Brain Stimulation. Recent advances in clinical BCI have focused on creating “closed-loop” systems. These systems rely on biomarker feedback and promise individualized therapy with optimal stimulation delivery and minimal side effects. Success of clinical BCI has paralleled research efforts to create BCI that restore upper extremity motor and sensory function to patients. Efforts to develop closed loop motor/sensory BCI is linked to the successes of today's clinical BCI.

AB - Implantable neurostimulation devices provide a direct therapeutic link to the nervous system and can be considered brain-computer interfaces (BCI). Under this definition, BCI are not simply science fiction, they are part of existing neurosurgical practice. Clinical BCI are standard of care for historically difficult to treat neurological disorders. These systems target the central and peripheral nervous system and include Vagus Nerve Stimulation, Responsive Neurostimulation, and Deep Brain Stimulation. Recent advances in clinical BCI have focused on creating “closed-loop” systems. These systems rely on biomarker feedback and promise individualized therapy with optimal stimulation delivery and minimal side effects. Success of clinical BCI has paralleled research efforts to create BCI that restore upper extremity motor and sensory function to patients. Efforts to develop closed loop motor/sensory BCI is linked to the successes of today's clinical BCI.

UR - http://www.scopus.com/inward/record.url?scp=85069809176&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85069809176&partnerID=8YFLogxK

U2 - 10.1016/j.jocn.2019.07.056

DO - 10.1016/j.jocn.2019.07.056

M3 - Review article

C2 - 31375306

AN - SCOPUS:85069809176

SN - 0967-5868

VL - 68

SP - 13

EP - 19

JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

ER -

Clinical neuroprosthetics: Today and tomorrow

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this