TY - JOUR
T1 - Familial exudative vitreoretinopathy mimicking persistent hyperplastic primary vitreous
AU - Chang-Godinich, Anne
AU - Paysse, Evelyn A.
AU - Coats, David K.
AU - Holz, Eric R.
N1 - Funding Information:
Supported in part by an unrestricted grant from Research to Prevent Blindness, Inc, New York, New York.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1999/4
Y1 - 1999/4
N2 - PURPOSE: To report an unusual case of familial exudative vitreoretinopathy in an infant. METHODS: Case report. A 6-day-old girl had unilateral microphthalmia in the right eye, with a retrolental plaque initially diagnosed as persistent hyperplastic primary vitreous. Three months later, peripheral retinal vascular changes and a fibrovascular ridge were noted in the left eye, suggesting familial exudative vitreoretinopathy as the cause in both eyes. RESULTS: The microphthalmic right eye was unsalvageable. The left eye developed an exudative retinal detachment despite photocoagulation of the peripheral avascular retina. Additional cryotherapy resulted in resolution of the detachment and regression of the vascular changes. CONCLUSIONS: With highly asymmetric involvement, neonatal familial exudative vitreoretinopathy can mimic persistent hyperplastic primary vitreous. Fellow eye involvement can progress rapidly.
AB - PURPOSE: To report an unusual case of familial exudative vitreoretinopathy in an infant. METHODS: Case report. A 6-day-old girl had unilateral microphthalmia in the right eye, with a retrolental plaque initially diagnosed as persistent hyperplastic primary vitreous. Three months later, peripheral retinal vascular changes and a fibrovascular ridge were noted in the left eye, suggesting familial exudative vitreoretinopathy as the cause in both eyes. RESULTS: The microphthalmic right eye was unsalvageable. The left eye developed an exudative retinal detachment despite photocoagulation of the peripheral avascular retina. Additional cryotherapy resulted in resolution of the detachment and regression of the vascular changes. CONCLUSIONS: With highly asymmetric involvement, neonatal familial exudative vitreoretinopathy can mimic persistent hyperplastic primary vitreous. Fellow eye involvement can progress rapidly.
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U2 - 10.1016/S0002-9394(99)00003-3
DO - 10.1016/S0002-9394(99)00003-3
M3 - Article
C2 - 10218708
AN - SCOPUS:0033119564
SN - 0002-9394
VL - 127
SP - 469
EP - 471
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 4
ER -