From molecular to modular cell biology

Leland H. Hartwell; John J. Hopfield; Stanislas Leibler; Andrew W. Murray

doi:10.1038/35011540

From molecular to modular cell biology

Leland H. Hartwell, John J. Hopfield, Stanislas Leibler, Andrew W. Murray

Houston Methodist

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2913 Scopus citations

Abstract

Cellular functions, such as signal transmission, are carried out by 'modules' made up of many species of interacting molecules. Understanding how modules work has depended on combining phenomenological analysis with molecular studies. General principles that govern the structure and behaviour of modules may be discovered with help from synthetic sciences such as engineering and computer science, from stronger interactions between experiment and theory in cell biology, and from an appreciation of evolutionary constraints.

Original language	English (US)
Pages (from-to)	C47-C52
Journal	Nature
Volume	402
Issue number	6761 SUPPL. 1
DOIs	https://doi.org/10.1038/35011540
State	Published - Dec 2 1999

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title = "From molecular to modular cell biology",

abstract = "Cellular functions, such as signal transmission, are carried out by 'modules' made up of many species of interacting molecules. Understanding how modules work has depended on combining phenomenological analysis with molecular studies. General principles that govern the structure and behaviour of modules may be discovered with help from synthetic sciences such as engineering and computer science, from stronger interactions between experiment and theory in cell biology, and from an appreciation of evolutionary constraints.",

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AU - Murray, Andrew W.

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From molecular to modular cell biology

Abstract

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