Melanocyte stem cell maintenance and hair graying

Eiríkur Steingrímsson; Neal G. Copeland; Nancy A. Jenkins

doi:10.1016/j.cell.2005.03.021

Melanocyte stem cell maintenance and hair graying

Eiríkur Steingrímsson, Neal G. Copeland, Nancy A. Jenkins

Research output: Contribution to journal › Short survey › peer-review

96 Scopus citations

Abstract

Hair graying is an obvious sign of human aging, yet little was known about its causes. Two recent papers provide compelling evidence that hair graying is due to incomplete melanocyte stem cell maintenance and identify Pax3 and Mitf as key molecules that help regulate the balance between melanocyte stem cell maintenance and differentiation.

Original language	English (US)
Pages (from-to)	9-12
Number of pages	4
Journal	Cell
Volume	121
Issue number	1
DOIs	https://doi.org/10.1016/j.cell.2005.03.021
State	Published - Apr 8 2005

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2005.03.021

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title = "Melanocyte stem cell maintenance and hair graying",

abstract = "Hair graying is an obvious sign of human aging, yet little was known about its causes. Two recent papers provide compelling evidence that hair graying is due to incomplete melanocyte stem cell maintenance and identify Pax3 and Mitf as key molecules that help regulate the balance between melanocyte stem cell maintenance and differentiation.",

author = "Eir{\'i}kur Steingr{\'i}msson and Copeland, {Neal G.} and Jenkins, {Nancy A.}",

year = "2005",

month = apr,

day = "8",

doi = "10.1016/j.cell.2005.03.021",

language = "English (US)",

volume = "121",

pages = "9--12",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "1",

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T1 - Melanocyte stem cell maintenance and hair graying

AU - Steingrímsson, Eiríkur

AU - Copeland, Neal G.

AU - Jenkins, Nancy A.

PY - 2005/4/8

Y1 - 2005/4/8

N2 - Hair graying is an obvious sign of human aging, yet little was known about its causes. Two recent papers provide compelling evidence that hair graying is due to incomplete melanocyte stem cell maintenance and identify Pax3 and Mitf as key molecules that help regulate the balance between melanocyte stem cell maintenance and differentiation.

AB - Hair graying is an obvious sign of human aging, yet little was known about its causes. Two recent papers provide compelling evidence that hair graying is due to incomplete melanocyte stem cell maintenance and identify Pax3 and Mitf as key molecules that help regulate the balance between melanocyte stem cell maintenance and differentiation.

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U2 - 10.1016/j.cell.2005.03.021

DO - 10.1016/j.cell.2005.03.021

M3 - Short survey

C2 - 15820674

AN - SCOPUS:17044364797

SN - 0092-8674

VL - 121

SP - 9

EP - 12

JO - Cell

JF - Cell

IS - 1

ER -

Melanocyte stem cell maintenance and hair graying

Abstract

ASJC Scopus subject areas

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