MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization

D. A. Herzka; M. S. Kotys; S. Krueger; B. J. Traughber; J. Heroux; A. M. Gharib; J. Ohayon; S. Weiss; R. I. Pettigrew; B. J. Wood

doi:10.1117/12.770758

MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization

D. A. Herzka, M. S. Kotys, S. Krueger, B. J. Traughber, J. Heroux, A. M. Gharib, J. Ohayon, S. Weiss, R. I. Pettigrew, B. J. Wood

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Excitation emission spectroscopy (EES) has been used in the past to characterize many different types of tissue. This technique uses multiple excitation wavelengths and samples a complete optical spectrum for each, yielding an excitation-emission matrix (EEM). Upon study of the EEM, it is possible to determine the presence of multiple optical contrast agents since these dyes can have characteristic spectra that can be separated. Here, we demonstrate EES specifically designed for use in conjunction with MR. This EES is applied with an in-suite control setup that permits real-time navigation, utilizing active MR tracking catheters, and providing a platform for MR-guided tissue characterization. The EES system is used in a demonstration experiment to highlight MR imaging, MR guidance in conjunction with a catheter-based optical measurement.

Original language	English (US)
Title of host publication	Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling
DOIs	https://doi.org/10.1117/12.770758
State	Published - 2008
Event	Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling - San Diego, CA, United States Duration: Feb 17 2008 → Feb 19 2008

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	6918
ISSN (Print)	1605-7422

Other

Other	Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling
Country/Territory	United States
City	San Diego, CA
Period	2/17/08 → 2/19/08

Keywords

Excitation-emission spectroscopy
In vivo tissue characterization
MR guidance
MR-guided tissue characterization
Tissue characterization

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.770758

Cite this

Herzka, D. A., Kotys, M. S., Krueger, S., Traughber, B. J., Heroux, J., Gharib, A. M., Ohayon, J., Weiss, S., Pettigrew, R. I., & Wood, B. J. (2008). MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization. In Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling Article 69181U (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6918). https://doi.org/10.1117/12.770758

MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization. / Herzka, D. A.; Kotys, M. S.; Krueger, S. et al.
Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling. 2008. 69181U (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6918).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Herzka, DA, Kotys, MS, Krueger, S, Traughber, BJ, Heroux, J, Gharib, AM, Ohayon, J, Weiss, S, Pettigrew, RI & Wood, BJ 2008, MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization. in Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling., 69181U, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 6918, Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling, San Diego, CA, United States, 2/17/08. https://doi.org/10.1117/12.770758

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title = "MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization",

abstract = "Excitation emission spectroscopy (EES) has been used in the past to characterize many different types of tissue. This technique uses multiple excitation wavelengths and samples a complete optical spectrum for each, yielding an excitation-emission matrix (EEM). Upon study of the EEM, it is possible to determine the presence of multiple optical contrast agents since these dyes can have characteristic spectra that can be separated. Here, we demonstrate EES specifically designed for use in conjunction with MR. This EES is applied with an in-suite control setup that permits real-time navigation, utilizing active MR tracking catheters, and providing a platform for MR-guided tissue characterization. The EES system is used in a demonstration experiment to highlight MR imaging, MR guidance in conjunction with a catheter-based optical measurement.",

keywords = "Excitation-emission spectroscopy, In vivo tissue characterization, MR guidance, MR-guided tissue characterization, Tissue characterization",

author = "Herzka, {D. A.} and Kotys, {M. S.} and S. Krueger and Traughber, {B. J.} and J. Heroux and Gharib, {A. M.} and J. Ohayon and S. Weiss and Pettigrew, {R. I.} and Wood, {B. J.}",

year = "2008",

doi = "10.1117/12.770758",

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series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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AU - Herzka, D. A.

AU - Kotys, M. S.

AU - Krueger, S.

AU - Traughber, B. J.

AU - Heroux, J.

AU - Gharib, A. M.

AU - Ohayon, J.

AU - Weiss, S.

AU - Pettigrew, R. I.

AU - Wood, B. J.

PY - 2008

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N2 - Excitation emission spectroscopy (EES) has been used in the past to characterize many different types of tissue. This technique uses multiple excitation wavelengths and samples a complete optical spectrum for each, yielding an excitation-emission matrix (EEM). Upon study of the EEM, it is possible to determine the presence of multiple optical contrast agents since these dyes can have characteristic spectra that can be separated. Here, we demonstrate EES specifically designed for use in conjunction with MR. This EES is applied with an in-suite control setup that permits real-time navigation, utilizing active MR tracking catheters, and providing a platform for MR-guided tissue characterization. The EES system is used in a demonstration experiment to highlight MR imaging, MR guidance in conjunction with a catheter-based optical measurement.

AB - Excitation emission spectroscopy (EES) has been used in the past to characterize many different types of tissue. This technique uses multiple excitation wavelengths and samples a complete optical spectrum for each, yielding an excitation-emission matrix (EEM). Upon study of the EEM, it is possible to determine the presence of multiple optical contrast agents since these dyes can have characteristic spectra that can be separated. Here, we demonstrate EES specifically designed for use in conjunction with MR. This EES is applied with an in-suite control setup that permits real-time navigation, utilizing active MR tracking catheters, and providing a platform for MR-guided tissue characterization. The EES system is used in a demonstration experiment to highlight MR imaging, MR guidance in conjunction with a catheter-based optical measurement.

KW - Excitation-emission spectroscopy

KW - In vivo tissue characterization

KW - MR guidance

KW - MR-guided tissue characterization

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SN - 9780819471024

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling

T2 - Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling

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ER -

MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization

Abstract

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Keywords

ASJC Scopus subject areas

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