Murine chromosomal location of four class iii pou transcription factors

Karen B. Avraham; Brian C. Cho; Debra Gilbert; Hideta Fujii; Koji Okamoto; Takuya Shimazaki; Toshiro Ito; Hiroki Shoji; Yoshio Wakamatsu; Hisato Kondoh; Naoki Takahashi; Masami Muramatsu; Hiroshi Hamada; Neal G. Copeland; Nancy A. Jenkins

doi:10.1006/geno.1993.1436

Murine chromosomal location of four class iii pou transcription factors

Karen B. Avraham, Brian C. Cho, Debra Gilbert, Hideta Fujii, Koji Okamoto, Takuya Shimazaki, Toshiro Ito, Hiroki Shoji, Yoshio Wakamatsu, Hisato Kondoh, Naoki Takahashi, Masami Muramatsu, Hiroshi Hamada, Neal G. Copeland, Nancy A. Jenkins

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A family of mouse genes encoding class III POU transcription factors consists of four members: Oct-6, Brn-2, Brn-1, and Brn-4. In accordance with mouse nomenclature, these loci have been designated Otf-6, Otf-7, Otf-8, and Otf-9, respectively. While the four genes share a highly conserved class III POU domain, the remaining regions are considerably diverged from each other. The POU domains of these transcription factors recognize the octamer-motif sequence and possess a similar DNA-binding specificity. Chromosomal mapping has demonstrated that the four genes are unlinked: Otf-6 is located on the distal region of chromosome 4, Otf-7 on the proximal region of chromosome 4, Otf-8 on chromosome 1, and Otf-9 on the X chromosome.

Original language	English (US)
Pages (from-to)	131-133
Number of pages	3
Journal	Genomics
Volume	18
Issue number	1
DOIs	https://doi.org/10.1006/geno.1993.1436
State	Published - Oct 1993

ASJC Scopus subject areas

Genetics

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@article{163200d447d44561ab5329f5c4ec0d16,

title = "Murine chromosomal location of four class iii pou transcription factors",

abstract = "A family of mouse genes encoding class III POU transcription factors consists of four members: Oct-6, Brn-2, Brn-1, and Brn-4. In accordance with mouse nomenclature, these loci have been designated Otf-6, Otf-7, Otf-8, and Otf-9, respectively. While the four genes share a highly conserved class III POU domain, the remaining regions are considerably diverged from each other. The POU domains of these transcription factors recognize the octamer-motif sequence and possess a similar DNA-binding specificity. Chromosomal mapping has demonstrated that the four genes are unlinked: Otf-6 is located on the distal region of chromosome 4, Otf-7 on the proximal region of chromosome 4, Otf-8 on chromosome 1, and Otf-9 on the X chromosome.",

author = "Avraham, {Karen B.} and Cho, {Brian C.} and Debra Gilbert and Hideta Fujii and Koji Okamoto and Takuya Shimazaki and Toshiro Ito and Hiroki Shoji and Yoshio Wakamatsu and Hisato Kondoh and Naoki Takahashi and Masami Muramatsu and Hiroshi Hamada and Copeland, {Neal G.} and Jenkins, {Nancy A.}",

year = "1993",

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doi = "10.1006/geno.1993.1436",

language = "English (US)",

volume = "18",

pages = "131--133",

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T1 - Murine chromosomal location of four class iii pou transcription factors

AU - Avraham, Karen B.

AU - Cho, Brian C.

AU - Gilbert, Debra

AU - Fujii, Hideta

AU - Okamoto, Koji

AU - Shimazaki, Takuya

AU - Ito, Toshiro

AU - Shoji, Hiroki

AU - Wakamatsu, Yoshio

AU - Kondoh, Hisato

AU - Takahashi, Naoki

AU - Muramatsu, Masami

AU - Hamada, Hiroshi

AU - Copeland, Neal G.

AU - Jenkins, Nancy A.

PY - 1993/10

Y1 - 1993/10

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AB - A family of mouse genes encoding class III POU transcription factors consists of four members: Oct-6, Brn-2, Brn-1, and Brn-4. In accordance with mouse nomenclature, these loci have been designated Otf-6, Otf-7, Otf-8, and Otf-9, respectively. While the four genes share a highly conserved class III POU domain, the remaining regions are considerably diverged from each other. The POU domains of these transcription factors recognize the octamer-motif sequence and possess a similar DNA-binding specificity. Chromosomal mapping has demonstrated that the four genes are unlinked: Otf-6 is located on the distal region of chromosome 4, Otf-7 on the proximal region of chromosome 4, Otf-8 on chromosome 1, and Otf-9 on the X chromosome.

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JO - Genomics

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Murine chromosomal location of four class iii pou transcription factors

Abstract

ASJC Scopus subject areas

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