Optimizing aortic valve prosthesis selection in patients with obesity: Institutional experience with multidisciplinary perspective

Ozan Onur Balkanay, Halil Ibrahim Bulut, Ergida Albrahimi, Miri Mirizade, Abdulgani Orhun Yenigün, Daniel Tomey, Jacques Bistre, Rodolfo J. Oviedo, Cigdem Tel Ustunisik, Berk Arapi, Deniz Goksedef, Suat Nail Omeroglu, Gokhan Ipek

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Aortic valve diseases are life-threatening conditions with increasing prevalence worldwide. Risk factors include gender, age, hypertension, dyslipidemia, and type 2 diabetes. Obesity is closely related to these risk factors and has been linked to a higher risk of developing aortic valve diseases. However, there is no specific guideline for managing aortic valve disease in patients with obesity, and the choice of valve type remains uncertain. Methods: A total of 130 patients with obesity who met the inclusion criteria underwent surgical aortic valve replacement. The patients were divided into two groups based on the type of prosthesis used. Among the study cohort, 50 patients received a bioprosthetic valve, while 80 patients received a mechanical valve. We compared these groups in terms of perioperative characteristics and follow-up results. Statistical significance was determined using a p-value threshold of 0.05. Results: There were no significant differences in age, gender, body mass index, or cardiac comorbidities between the two groups. Preoperative blood results and echo findings also showed no significant differences. Intraoperative characteristics and postoperative outcomes, including mortality and acute kidney injury, did not differ significantly between the groups. In addition, BHVG patients had shorter ICU stays compared to MHVG patients without significance. Conclusion: Deliberate consideration is crucial when selecting valves for obese patients, particularly those with class II obesity. This is due to the potential influence of obesity on valve types, as well as the need to account for the possibility of bariatric surgery and its potential effects.

Original languageEnglish (US)
Pages (from-to)667-674
Number of pages8
JournalAsian Cardiovascular and Thoracic Annals
Volume31
Issue number8
DOIs
StatePublished - Oct 2023

Keywords

  • Aortic valve
  • bioprosthetic
  • blood
  • cardiac
  • coagulation/anticoagulation
  • eg
  • etc.)
  • heart valve prosthesis (specify type
  • mechanical
  • obesity (incl related subjects)
  • replacement

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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