Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type

Francis J. Pirozzolo; David S. Baskin; Andrew A. Swihart; Stanley H. Appel; N. Herrmann; J. Sadavoy; A. Steingart; Gary W. Small; J. Edward Spar; Daniel A. Plotkin; Michael Kopelman; Pierre N. Tariot; Eric D. Caine; William K. Summers; Lawrence V. Majovski; Gary M. Marsh; Kenneth Tachiki; Arthur Kling

doi:10.1056/NEJM198706183162512

Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type

Francis J. Pirozzolo, David S. Baskin, Andrew A. Swihart, Stanley H. Appel, N. Herrmann, J. Sadavoy, A. Steingart, Gary W. Small, J. Edward Spar, Daniel A. Plotkin, Michael Kopelman, Pierre N. Tariot, Eric D. Caine, William K. Summers, Lawrence V. Majovski, Gary M. Marsh, Kenneth Tachiki, Arthur Kling

Research output: Contribution to journal › Letter › peer-review

24 Scopus citations

Abstract

To the Editor: The report by Summers et a!. (Nov. 13 issue)* contains methodologic problems that render the results difficult to interpret. First, the selection of outcome variables is inappropriate. The neuropsychological assessment techniques employed included the Luria–Nebraska Neuropsychological Test, the Minnesota Multiphasic Personality Inventory, the New York University Memory Test, Wechsler's Adult Intelligence Scale, the Mini Mental State test, three psychometric tests, and a subjective measure designed by the authors. The authors do not refer to the results of any tests except the four they designed. The psychometric properties and construct validity of these psychometric scales are unknown. It…

Original language	English (US)
Pages (from-to)	1603-1605
Number of pages	3
Journal	New England Journal of Medicine
Volume	316
Issue number	25
DOIs	https://doi.org/10.1056/NEJM198706183162512
State	Published - Jun 18 1987

ASJC Scopus subject areas

General Medicine

Access to Document

10.1056/NEJM198706183162512

Cite this

Pirozzolo, F. J., Baskin, D. S., Swihart, A. A., Appel, S. H., Herrmann, N., Sadavoy, J., Steingart, A., Small, G. W., Spar, J. E., Plotkin, D. A., Kopelman, M., Tariot, P. N., Caine, E. D., Summers, W. K., Majovski, L. V., Marsh, G. M., Tachiki, K., & Kling, A. (1987). Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type. New England Journal of Medicine, 316(25), 1603-1605. https://doi.org/10.1056/NEJM198706183162512

Pirozzolo, FJ, Baskin, DS, Swihart, AA, Appel, SH, Herrmann, N, Sadavoy, J, Steingart, A, Small, GW, Spar, JE, Plotkin, DA, Kopelman, M, Tariot, PN, Caine, ED, Summers, WK, Majovski, LV, Marsh, GM, Tachiki, K & Kling, A 1987, 'Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type', New England Journal of Medicine, vol. 316, no. 25, pp. 1603-1605. https://doi.org/10.1056/NEJM198706183162512

@article{b8274dc46a284e9dba139ca22114c50f,

title = "Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type",

abstract = "To the Editor: The report by Summers et a!. (Nov. 13 issue)* contains methodologic problems that render the results difficult to interpret. First, the selection of outcome variables is inappropriate. The neuropsychological assessment techniques employed included the Luria–Nebraska Neuropsychological Test, the Minnesota Multiphasic Personality Inventory, the New York University Memory Test, Wechsler's Adult Intelligence Scale, the Mini Mental State test, three psychometric tests, and a subjective measure designed by the authors. The authors do not refer to the results of any tests except the four they designed. The psychometric properties and construct validity of these psychometric scales are unknown. It…",

author = "Pirozzolo, {Francis J.} and Baskin, {David S.} and Swihart, {Andrew A.} and Appel, {Stanley H.} and N. Herrmann and J. Sadavoy and A. Steingart and Small, {Gary W.} and Spar, {J. Edward} and Plotkin, {Daniel A.} and Michael Kopelman and Tariot, {Pierre N.} and Caine, {Eric D.} and Summers, {William K.} and Majovski, {Lawrence V.} and Marsh, {Gary M.} and Kenneth Tachiki and Arthur Kling",

year = "1987",

month = jun,

day = "18",

doi = "10.1056/NEJM198706183162512",

language = "English (US)",

volume = "316",

pages = "1603--1605",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachusetts Medical Society",

number = "25",

}

TY - JOUR

T1 - Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type

AU - Pirozzolo, Francis J.

AU - Baskin, David S.

AU - Swihart, Andrew A.

AU - Appel, Stanley H.

AU - Herrmann, N.

AU - Sadavoy, J.

AU - Steingart, A.

AU - Small, Gary W.

AU - Spar, J. Edward

AU - Plotkin, Daniel A.

AU - Kopelman, Michael

AU - Tariot, Pierre N.

AU - Caine, Eric D.

AU - Summers, William K.

AU - Majovski, Lawrence V.

AU - Marsh, Gary M.

AU - Tachiki, Kenneth

AU - Kling, Arthur

PY - 1987/6/18

Y1 - 1987/6/18

N2 - To the Editor: The report by Summers et a!. (Nov. 13 issue)* contains methodologic problems that render the results difficult to interpret. First, the selection of outcome variables is inappropriate. The neuropsychological assessment techniques employed included the Luria–Nebraska Neuropsychological Test, the Minnesota Multiphasic Personality Inventory, the New York University Memory Test, Wechsler's Adult Intelligence Scale, the Mini Mental State test, three psychometric tests, and a subjective measure designed by the authors. The authors do not refer to the results of any tests except the four they designed. The psychometric properties and construct validity of these psychometric scales are unknown. It…

AB - To the Editor: The report by Summers et a!. (Nov. 13 issue)* contains methodologic problems that render the results difficult to interpret. First, the selection of outcome variables is inappropriate. The neuropsychological assessment techniques employed included the Luria–Nebraska Neuropsychological Test, the Minnesota Multiphasic Personality Inventory, the New York University Memory Test, Wechsler's Adult Intelligence Scale, the Mini Mental State test, three psychometric tests, and a subjective measure designed by the authors. The authors do not refer to the results of any tests except the four they designed. The psychometric properties and construct validity of these psychometric scales are unknown. It…

UR - http://www.scopus.com/inward/record.url?scp=0023235931&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023235931&partnerID=8YFLogxK

U2 - 10.1056/NEJM198706183162512

DO - 10.1056/NEJM198706183162512

M3 - Letter

C2 - 3587295

AN - SCOPUS:0023235931

SN - 0028-4793

VL - 316

SP - 1603

EP - 1605

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 25

ER -

Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this