Research output per year
Research output per year
- 22 results
Search results
-
2024
Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma
Deutzmann, A., Sullivan, D. K., Dhanasekaran, R., Li, W., Chen, X., Tong, L., Mahauad-Fernandez, W. D., Bell, J., Mosley, A., Koehler, A. N., Li, Y. & Felsher, D. W., Dec 2024, In: Nature Communications. 15, 1, 963.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters
Liu, Y., Azizian, N. G., Sullivan, D. K. & Li, Y., Dec 2022, In: Nature Communications. 13, 1, 7047.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters
Liu, Y., Azizian, N. G., Sullivan, D. K. & Li, Y., Nov 17 2022, In: Nature Communications. 7047.Research output: Contribution to journal › Article › peer-review
Open Access -
mTOR is a major determinant of chemosensitivity
Liu, Y., Azizian, N. G., Sullivan, D. K. & Li, Y., Jan 21 2022, (Unpublished) In: bioRxiv.Research output: Contribution to journal › Article
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2021
Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells
Du, R., Sullivan, D. K., Azizian, N. G., Liu, Y. & Li, Y., Mar 6 2021, In: BMC Cancer. 21, 1, p. 237 13 p., 237.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2020
Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo
Azizian, N. G., Sullivan, D. K., Nie, L., Pardo, S., Molleur, D., Chen, J., Weintraub, S. T. & Li, Y., Dec 8 2020, (E-pub ahead of print) In: Journal of Proteome Research.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2019
Mebendazole for Differentiation Therapy of Acute Myeloid Leukemia Identified by a Lineage Maturation Index
Li, Y., Thomas, D., Deutzmann, A., Majeti, R., Felsher, D. W. & Dill, D. L., Nov 14 2019, In: Scientific Reports. 9, 1, p. 16775Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Rational targeted therapeutics for double-hit lymphoma
Azizian, N. G., Liu, Y., Pham, L. V. & Li, Y., Aug 21 2019, In: International Journal of Hematologic Oncology. 8, 3, p. IJH19Research output: Contribution to journal › Article › peer-review
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Simultaneous targeting of XPO1 and BCL2 as an effective treatment strategy for double-hit lymphoma
Liu, Y., Azizian, N. G., Dou, Y., Pham, L. V. & Li, Y., Nov 21 2019, In: Journal of Hematology and Oncology. 12, 1Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2016
BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia
Li, Y., Deutzmann, A., Choi, P. S., Fan, A. C. & Felsher, D. W., May 10 2016, In: Oncotarget. 7, 19, p. 26926-26934 9 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
MYC regulates the antitumor immune response through CD47 and PD-L1
Casey, S. C., Tong, L., Li, Y., Do, R., Walz, S., Fitzgerald, K. N., Gouw, A. M., Baylot, V., Gütgemann, I., Eilers, M. & Felsher, D. W., Apr 8 2016, In: Science. 352, 6282, p. 227-231 5 p.Research output: Contribution to journal › Article › peer-review
Open Access930 Scopus citations -
2015
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism
Shroff, E. H., Eberlin, L. S., Dang, V. M., Gouw, A. M., Gabay, M., Adam, S. J., Bellovin, D. I., Trand, P. T., Philbrick, W. M., Garcia-Ocana, A., Casey, S. C., Li, Y., Dang, C. V., Zare, R. N. & Felsher, D. W., May 26 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 21, p. 6539-6544 6 p.Research output: Contribution to journal › Article › peer-review
Open Access187 Scopus citations -
2014
Activation of cre recombinase alone can induce complete tumor regression
Li, Y., Choi, P. S., Casey, S. C. & Felsher, D. W., Sep 2014, In: PLoS ONE. 9, 9, e0107589.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance
Choi, P. S., Li, Y. & Felsher, D. W., Aug 12 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 32, p. E3316-E3324Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Inactivation of MYC reverses tumorigenesis
Li, Y., Casey, S. C. & Felsher, D. W., Jul 1 2014, In: Journal of Internal Medicine. 276, 1, p. 52-60 9 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
miR-17–92 explains MYC oncogene addiction
Li, Y., Casey, S. C., Choi, P. S. & Felsher, D. W., Dec 8 2014, In: Molecular and Cellular Oncology. 1, 4, e970092.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
MYC activation is a hallmark of cancer initiation and maintenance
Gabay, M., Li, Y. & Felsher, D. W., 2014, In: Cold Spring Harbor Perspectives in Medicine. 4, 6Research output: Contribution to journal › Article › peer-review
Open Access572 Scopus citations -
MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a Neoplastic state
Li, Y., Choi, P. S., Casey, S. C., Dill, D. L. & Felsher, D. W., Aug 11 2014, In: Cancer Cell. 26, 2, p. 262-272 11 p.Research output: Contribution to journal › Article › peer-review
Open Access148 Scopus citations -
2007
PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice
Iida, K., Li, Y., McGrath, B. C., Frank, A. & Cavener, D. R., Aug 29 2007, In: BMC Cell Biology. 8, 38.Research output: Contribution to journal › Article › peer-review
Open Access75 Scopus citations -
2006
PERK EIF2AK3 control of pancreatic β cell differentiation and proliferation is required for postnatal glucose homeostasis
Zhang, W., Feng, D., Li, Y., Iida, K., McGrath, B. & Cavener, D. R., Dec 2006, In: Cell Metabolism. 4, 6, p. 491-497 7 p.Research output: Contribution to journal › Article › peer-review
Open Access229 Scopus citations -
2005
Proinsulin disulfide maturation and misfolding in the endoplasmic reticulum
Liu, M., Li, Y., Cavener, D. & Arvan, P., Apr 8 2005, In: Journal of Biological Chemistry. 280, 14, p. 13209-13212 4 p.Research output: Contribution to journal › Article › peer-review
Open Access97 Scopus citations -
2003
PERK eIF2α kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver
Li, Y., Iida, K., O'Neil, J., Zhang, P., Li, S., Frank, A., Gabai, A., Zambito, F., Liang, S. H., Rosen, C. J. & Cavener, D. R., Aug 1 2003, In: Endocrinology. 144, 8, p. 3505-3513 9 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations