@inproceedings{a6a73d55d8db414787e50b11831411be,
title = "A 96-well, plate-based microfluidic device for multiplexed chemosensitivity testing on intact tissues",
abstract = "This paper reports the development of a novel drug testing platform that uses intact tumor tissue in a 96-well, plate- based microfluidic device. This device was reported at μTAS12 [1]. Here, we incorporate a new eulture membrane transfer technique that enables the culture, drug exposure, and post-exposure tissue processing to be separated into three platforms (Fig. la-c). The result of our Tcmozolomide(TMZ) drug testing on Glioblastoma Multiforme (GBM) xenograft sliccs demonstrate the feasibility of using this platform to identify effective chcmotherapcutic drugs for specific tumors and patients to guide therapeutic decision-making.",
keywords = "Cancer, Microfluidics, Organotypic slice culture, Personalized chemotherapy, Tumor",
author = "T. Chang and Mikheev, {A. M.} and Monnat, {R. J.} and Rostomily, {R. C.} and A. Folch",
year = "2013",
language = "English (US)",
isbn = "9781632666246",
series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
publisher = "Chemical and Biological Microsystems Society",
pages = "506--508",
booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",
}