TY - GEN
T1 - A comprehensive review of 4d flow MRI and CFD in cardiovascular and congenital heart disease
AU - Nihum, Lamees El
AU - Chinnadurai, Ponraj
AU - Huie Lin, C.
AU - Banerjee, Debjyoti
N1 - Funding Information:
Lamees El Nihum was supported by a Burroughs Wellcome Fund Physician Scientist Award to the Texas A&M University Academy of Physician Scientists.
Publisher Copyright:
© 2021 by ASME.
PY - 2021
Y1 - 2021
N2 - A growing population of adults with congenital heart disease (CHD) has spurred increased study in recent decades into the complex anatomical vasculature of congenital heart patients and the resulting hemodynamic changes that progressively affect the heart and great vessels. To this end, assessment of flow dynamics using advanced imaging technology and computational simulations have paved a path toward greater understanding of the patterns and implications of flow alterations in complex and changing vasculature, and offer promise for diagnostic and therapeutic intervention in the future. The focus of this review is to describe past studies of fourdimensional (4D) magnetic resonance imaging (MRI) and computational fluid dynamics (CFD) in the literature as related to pathophysiology of the heart in structural and CHD. This review will highlight the importance of working with both imaging and simulation technology to co-validate experimental (4D MRI) and simulation (CFD) models, allowing for more accurate depiction of flow dynamics within human vasculature and ultimately toward improvement of the tools and methodologies used in analysis, simulation and prediction of cardiovascular hemodynamics toward enhanced diagnostics and therapeutic intervention.
AB - A growing population of adults with congenital heart disease (CHD) has spurred increased study in recent decades into the complex anatomical vasculature of congenital heart patients and the resulting hemodynamic changes that progressively affect the heart and great vessels. To this end, assessment of flow dynamics using advanced imaging technology and computational simulations have paved a path toward greater understanding of the patterns and implications of flow alterations in complex and changing vasculature, and offer promise for diagnostic and therapeutic intervention in the future. The focus of this review is to describe past studies of fourdimensional (4D) magnetic resonance imaging (MRI) and computational fluid dynamics (CFD) in the literature as related to pathophysiology of the heart in structural and CHD. This review will highlight the importance of working with both imaging and simulation technology to co-validate experimental (4D MRI) and simulation (CFD) models, allowing for more accurate depiction of flow dynamics within human vasculature and ultimately toward improvement of the tools and methodologies used in analysis, simulation and prediction of cardiovascular hemodynamics toward enhanced diagnostics and therapeutic intervention.
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U2 - 10.1115/FEDSM2021-65886
DO - 10.1115/FEDSM2021-65886
M3 - Conference contribution
AN - SCOPUS:85116924381
T3 - American Society of Mechanical Engineers, Fluids Engineering Division (Publication) FEDSM
BT - Aerospace Engineering Division Joint Track; Computational Fluid Dynamics
PB - American Society of Mechanical Engineers (ASME)
T2 - ASME 2021 Fluids Engineering Division Summer Meeting, FEDSM 2021
Y2 - 10 August 2021 through 12 August 2021
ER -