TY - GEN
T1 - A framework for building multi-tissue atlas of zebrafish embryo
AU - Le, Yen H.
AU - Ducharme, Nicole
AU - Bondesson, Maria
AU - Kakadiaris, Ioannis A.
N1 - Publisher Copyright:
© 2014 IEEE.
PY - 2014/7/29
Y1 - 2014/7/29
N2 - This paper presents a new framework for building a representative atlas of multiple tissue types for zebrafish embryos. In our framework, multiple normalization strategies were considered and evaluated. Moreover, to keep the resulting atlas representative, outlier samples were discovered and removed automatically. Our quality measure for multiple tissue channels was used for selecting the best resulting atlas and for driving the normalization process (to reduce the number of experiments). We applied our framework to computing a 2D atlas of five tissue types (vasculature, sensory neuronal precursors, somites, motor neurons, and yolk) from a population of 40 zebrafish embryos.
AB - This paper presents a new framework for building a representative atlas of multiple tissue types for zebrafish embryos. In our framework, multiple normalization strategies were considered and evaluated. Moreover, to keep the resulting atlas representative, outlier samples were discovered and removed automatically. Our quality measure for multiple tissue channels was used for selecting the best resulting atlas and for driving the normalization process (to reduce the number of experiments). We applied our framework to computing a 2D atlas of five tissue types (vasculature, sensory neuronal precursors, somites, motor neurons, and yolk) from a population of 40 zebrafish embryos.
KW - Multichannel atlas
KW - Tissue atlas
KW - Zebrafish
UR - http://www.scopus.com/inward/record.url?scp=84927929192&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84927929192&partnerID=8YFLogxK
U2 - 10.1109/isbi.2014.6867979
DO - 10.1109/isbi.2014.6867979
M3 - Conference contribution
AN - SCOPUS:84927929192
T3 - 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
SP - 750
EP - 753
BT - 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
Y2 - 29 April 2014 through 2 May 2014
ER -