A framework for building multi-tissue atlas of zebrafish embryo

Yen H. Le, Nicole Ducharme, Maria Bondesson, Ioannis A. Kakadiaris

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents a new framework for building a representative atlas of multiple tissue types for zebrafish embryos. In our framework, multiple normalization strategies were considered and evaluated. Moreover, to keep the resulting atlas representative, outlier samples were discovered and removed automatically. Our quality measure for multiple tissue channels was used for selecting the best resulting atlas and for driving the normalization process (to reduce the number of experiments). We applied our framework to computing a 2D atlas of five tissue types (vasculature, sensory neuronal precursors, somites, motor neurons, and yolk) from a population of 40 zebrafish embryos.

Original languageEnglish (US)
Title of host publication2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages750-753
Number of pages4
ISBN (Electronic)9781467319591
DOIs
StatePublished - Jul 29 2014
Event2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014 - Beijing, China
Duration: Apr 29 2014May 2 2014

Publication series

Name2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014

Conference

Conference2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
Country/TerritoryChina
CityBeijing
Period4/29/145/2/14

Keywords

  • Multichannel atlas
  • Tissue atlas
  • Zebrafish

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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