@inproceedings{6e8ca028ab924890830775fb337b81b0,
title = "A Method for Deciphering Major Drivers of Bacterial Iron Stress Response in the Presence of Oxidative Stressors",
abstract = "This paper describes a method for deciphering major drivers of bacterial stress response using an empirically informed computational approach. We develop a working model of iron flux regulation and concomitant oxidative stress response in Escherichia coli. The integrated model is used to investigate the temporal effects of iron and hydrogen peroxide stress on bacterial growth and metabolism. We employ a sensitivity analysis platform and, using various measures, probe for major mechanistic drivers of the bacterial response to iron stress.",
author = "Ajuzie, {Daniel C.} and Arshad, {Seyed A.} and Rasaputra, {Komal S.} and May, {Elebeoba E.}",
note = "Publisher Copyright: {\textcopyright} 2020 IEEE.; 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020 ; Conference date: 20-07-2020 Through 24-07-2020",
year = "2020",
month = jul,
doi = "10.1109/EMBC44109.2020.9176518",
language = "English (US)",
series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "2266--2269",
booktitle = "42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society",
address = "United States",
}