TY - GEN
T1 - A new snake algorithm to track neuronal structure in microscopy image
AU - Cheng, Jie
AU - Xu, Xiaoyin
AU - Cai, Hongmin
AU - Miller, Eric L.
AU - Wong, Stephen T.
PY - 2005
Y1 - 2005
N2 - We present a new method using snake to segment elongated objects in optical microscopy image. Such objects include neuronal dendrites, which play an important role in regulating neurological function and have manifest changes in many neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Based on our experience, standard gradient vector flow (GVF) snake has problem to track dendrites. The snake tends to stop too early due to the inhomogeneity of the dendrite signal. In the new method, we introduced an additional external force that aims to restart the region growing process and increase the capture range of the GVF snake. We tested the new method on real neuronal images and obtained better segmentation results. We demonstrate the performance of our method by examples.
AB - We present a new method using snake to segment elongated objects in optical microscopy image. Such objects include neuronal dendrites, which play an important role in regulating neurological function and have manifest changes in many neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Based on our experience, standard gradient vector flow (GVF) snake has problem to track dendrites. The snake tends to stop too early due to the inhomogeneity of the dendrite signal. In the new method, we introduced an additional external force that aims to restart the region growing process and increase the capture range of the GVF snake. We tested the new method on real neuronal images and obtained better segmentation results. We demonstrate the performance of our method by examples.
UR - http://www.scopus.com/inward/record.url?scp=33847208536&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33847208536&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:33847208536
SN - 0780392663
SN - 9780780392663
T3 - Proceedings of 2005 International Symposium on Intelligent Signal Processing and Communication Systems, ISPACS 2005
SP - 537
EP - 540
BT - Proceedings of 2005 International Symposium on Intelligent Signal Processing and Communication Systems, ISPACS 2005
T2 - 2005 International Symposium on Intelligent Signal Processing and Communication Systems, ISPACS 2005
Y2 - 13 December 2005 through 16 December 2005
ER -