Acquired haemophilia as a paraneoplastic manifestation of pancreatic cancer

Abeer Arain; Ibrahim N. Muhsen; Maen Abdelrahim

doi:10.3332/ECANCER.2020.1053

Acquired haemophilia as a paraneoplastic manifestation of pancreatic cancer

Abeer Arain, Ibrahim N. Muhsen, Maen Abdelrahim

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Acquired haemophilia is a severe haematological disorder characterised by the presence of anti-factor VIII antibodies. Although rare, it can lead to serious bleeding complications. Acquired haemophilia can be seen in patients with malignancies as a paraneoplastic phenomenon. This is a case of a 52-year-old patient who presented with haematuria and retroperitoneal bleeding soon after being diagnosed with pancreatic adenocarcinoma and subsequently was found to have acquired haemophilia. The treatment of underlying malignancy with chemotherapy may accelerate the eradication of anti-factor VIII antibodies.

Original language	English (US)
Article number	1053
Pages (from-to)	1053
Journal	ecancermedicalscience
Volume	14
DOIs	https://doi.org/10.3332/ECANCER.2020.1053
State	Published - Jun 4 2020

Keywords

Acquired haemophilia
Inhibitor treatment
Pancreatic cancer
Paraneoplastic phenomenon

ASJC Scopus subject areas

Oncology
Cancer Research

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10.3332/ECANCER.2020.1053

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abstract = "Acquired haemophilia is a severe haematological disorder characterised by the presence of anti-factor VIII antibodies. Although rare, it can lead to serious bleeding complications. Acquired haemophilia can be seen in patients with malignancies as a paraneoplastic phenomenon. This is a case of a 52-year-old patient who presented with haematuria and retroperitoneal bleeding soon after being diagnosed with pancreatic adenocarcinoma and subsequently was found to have acquired haemophilia. The treatment of underlying malignancy with chemotherapy may accelerate the eradication of anti-factor VIII antibodies.",

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Acquired haemophilia as a paraneoplastic manifestation of pancreatic cancer

Abstract

Keywords

ASJC Scopus subject areas

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