TY - JOUR
T1 - Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation
AU - Suh, Annie
AU - Pham, Anthony
AU - Cress, Mikel Jean
AU - Pincelli, Thais
AU - TerKonda, Sarvam P.
AU - Bruce, Alison J.
AU - Zubair, Abba C.
AU - Wolfram, Joy
AU - Shapiro, Shane A.
N1 - Funding Information:
This work was supported by Mayo Clinic . Among various sources of intramural funding, the authors particularly acknowledge support from the Center for Regenerative Medicine and Mayo Clinic Florida Focused Research Team Program .
Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/9
Y1 - 2019/9
N2 - Cellular and cell-derived components of adipose-derived tissue for the purposes of dermatologic and aesthetic rejuvenation applications have become increasingly studied and integrated into clinical practice. These components include micro-fragmented fat (nanofat), the stromal vascular fraction (SVF), adipose-derived mesenchymal stem cells (ASC), and extracellular vesicles (EVs), which have all shown capability to repair, regenerate, and rejuvenate surrounding tissue. Various aesthetic applications including hair growth, scar reduction, skin ischemia-reperfusion recovery, and facial rejuvenation are reviewed. In particular, results from preclinical and clinical studies are discussed, with a focus on clarification of nomenclature.
AB - Cellular and cell-derived components of adipose-derived tissue for the purposes of dermatologic and aesthetic rejuvenation applications have become increasingly studied and integrated into clinical practice. These components include micro-fragmented fat (nanofat), the stromal vascular fraction (SVF), adipose-derived mesenchymal stem cells (ASC), and extracellular vesicles (EVs), which have all shown capability to repair, regenerate, and rejuvenate surrounding tissue. Various aesthetic applications including hair growth, scar reduction, skin ischemia-reperfusion recovery, and facial rejuvenation are reviewed. In particular, results from preclinical and clinical studies are discussed, with a focus on clarification of nomenclature.
KW - Adipose
KW - Extracellular vesicles
KW - Mesenchymal stem cells
KW - Nanofat
KW - Regenerative medicine
KW - Stromal vascular fraction
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U2 - 10.1016/j.arr.2019.100933
DO - 10.1016/j.arr.2019.100933
M3 - Review article
C2 - 31247326
AN - SCOPUS:85067850008
SN - 1568-1637
VL - 54
JO - Ageing Research Reviews
JF - Ageing Research Reviews
M1 - 100933
ER -