Abstract
Antineoplastic therapy can be associated with drug-induced lung toxicity. With the increasing use of amiodarone for cardiac dysrhythmias there is an increasing possibility of its combined use with chemotherapies for various malignancies. We report a patient on long-term amiodarone who developed biopsy-proven drug-induced lung toxicity after receiving high-dose cyclophosphamide, at a time-frame much shorter than would have been predicted with cyclophosphamide alone. The potential for enhanced lung toxicity secondary to combination of amiodarone and cyclophosphamide is discussed.
Original language | English (US) |
---|---|
Pages (from-to) | 1109-1111 |
Number of pages | 3 |
Journal | Bone Marrow Transplantation |
Volume | 27 |
Issue number | 10 |
DOIs | |
State | Published - 2001 |
Keywords
- Amiodarone
- Cyclophosphamide
- Drug-induced lung toxicity
- Interstitial pneumonitis
- Oxidative stress
ASJC Scopus subject areas
- Hematology
- Transplantation