Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis

Erika N Guerrero; Joy Mitra; Haibo Wang; Suganya Rangaswamy; Pavana M Hegde; Priyadarshini Basu; K S Rao; Muralidhar L Hegde

doi:10.1093/hmg/ddz141

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis

Erika N Guerrero, Joy Mitra, Haibo Wang, Suganya Rangaswamy, Pavana M Hegde, Priyadarshini Basu, K S Rao, Muralidhar L Hegde

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Original language	English (US)
Pages (from-to)	3161-3162
Number of pages	2
Journal	Human Molecular Genetics
Volume	28
Issue number	18
DOIs	https://doi.org/10.1093/hmg/ddz141
State	Published - Sep 15 2019

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10.1093/hmg/ddz141

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Guerrero, E. N., Mitra, J., Wang, H., Rangaswamy, S., Hegde, P. M., Basu, P., Rao, K. S., & Hegde, M. L. (2019). Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis. Human Molecular Genetics, 28(18), 3161-3162. https://doi.org/10.1093/hmg/ddz141

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis. / Guerrero, Erika N; Mitra, Joy; Wang, Haibo et al.
In: Human Molecular Genetics, Vol. 28, No. 18, 15.09.2019, p. 3161-3162.

Research output: Contribution to journal › Article › peer-review

Guerrero, EN, Mitra, J, Wang, H, Rangaswamy, S, Hegde, PM, Basu, P, Rao, KS & Hegde, ML 2019, 'Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis', Human Molecular Genetics, vol. 28, no. 18, pp. 3161-3162. https://doi.org/10.1093/hmg/ddz141

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