Abstract
Pharmaceutical uses of cancer therapeutics, such as intravenous thrombin to elicit blood coagulation, have been hampered by lack of tumor specificity. Based on rapid progress in DNA origami-based machines capable of transporting molecular payloads, DNA nanorobots have been constructed to specifically deliver therapeutic agents into tumor vessels.
Original language | English (US) |
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Pages (from-to) | 573-577 |
Number of pages | 5 |
Journal | Trends in Biotechnology |
Volume | 37 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2019 |
Keywords
- DNA nanorobot
- active tumor targeting
- thrombin
- vascular infarction
ASJC Scopus subject areas
- Biotechnology
- Bioengineering