TY - JOUR
T1 - Antimicrobial Resistance
T2 - An Antimicrobial/Diagnostic Stewardship and Infection Prevention Approach
AU - Septimus, Edward Joel
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/9
Y1 - 2018/9
N2 - Antimicrobial resistance (AR) is one of the most serious public health threats today, which has been accelerated by the overuse and misuse of antimicrobials in humans and animals plus inadequate infection prevention. Numerous studies have shown a relationship between antimicrobial use and resistance. Antimicrobial stewardship (AS) programs have been shown to improve patient outcomes, reduce antimicrobial adverse events, and decrease AR. AS programs, when implemented alongside infection control measures, especially hand-hygiene interventions, were more effective than implementation of AS alone. Targeted coordination and prevention strategies are critical to stopping the spread of multidrug-resistant organisms.
AB - Antimicrobial resistance (AR) is one of the most serious public health threats today, which has been accelerated by the overuse and misuse of antimicrobials in humans and animals plus inadequate infection prevention. Numerous studies have shown a relationship between antimicrobial use and resistance. Antimicrobial stewardship (AS) programs have been shown to improve patient outcomes, reduce antimicrobial adverse events, and decrease AR. AS programs, when implemented alongside infection control measures, especially hand-hygiene interventions, were more effective than implementation of AS alone. Targeted coordination and prevention strategies are critical to stopping the spread of multidrug-resistant organisms.
KW - Antimicrobial resistance
KW - Antimicrobial stewardship
KW - Audit and feedback
KW - De-escalation
KW - Diagnostic stewardship
UR - http://www.scopus.com/inward/record.url?scp=85048949033&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85048949033&partnerID=8YFLogxK
U2 - 10.1016/j.mcna.2018.04.005
DO - 10.1016/j.mcna.2018.04.005
M3 - Review article
C2 - 30126573
AN - SCOPUS:85048949033
SN - 0025-7125
VL - 102
SP - 819
EP - 829
JO - Medical Clinics of North America
JF - Medical Clinics of North America
IS - 5
ER -