Autophagy and alzheimer’s disease

Sheng Chen; Qinming Zhou; You Ni; Weidong Le

doi:10.1007/978-981-15-4272-5_1

Autophagy and alzheimer’s disease

Sheng Chen, Qinming Zhou, You Ni, Weidong Le

Research output: Chapter in Book/Report/Conference proceeding › Chapter

10 Scopus citations

Abstract

Alzheimer’s disease (AD) is the most common type of dementia and is characterized by progressive cognitive decline. Increasing evidence has demonstrated that the autophagic process plays an important role in AD. In this chapter, we will discuss the role of autophagy in the pathogenesis of AD and other types of dementia, including dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), vascular dementia (VD) and prion diseases. In addition, we will discuss autophagy-targeted therapies as future treatments for AD.

Original language	English (US)
Title of host publication	Advances in Experimental Medicine and Biology
Publisher	Springer
Pages	3-19
Number of pages	17
Volume	1207
DOIs	https://doi.org/10.1007/978-981-15-4272-5_1
State	Published - 2020

Publication series

Name	Advances in experimental medicine and biology
Publisher	Springer New York
ISSN (Print)	0065-2598

Keywords

Alzheimer’s disease
Autophagy
Dementia
Frontotemporal Dementia
Humans
Dementia, Vascular
Lewy Body Disease
Alzheimer Disease

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-981-15-4272-5_1

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title = "Autophagy and alzheimer{\textquoteright}s disease",

abstract = "Alzheimer{\textquoteright}s disease (AD) is the most common type of dementia and is characterized by progressive cognitive decline. Increasing evidence has demonstrated that the autophagic process plays an important role in AD. In this chapter, we will discuss the role of autophagy in the pathogenesis of AD and other types of dementia, including dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), vascular dementia (VD) and prion diseases. In addition, we will discuss autophagy-targeted therapies as future treatments for AD.",

keywords = "Alzheimer{\textquoteright}s disease, Autophagy, Dementia, Frontotemporal Dementia, Humans, Dementia, Vascular, Lewy Body Disease, Alzheimer Disease",

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T1 - Autophagy and alzheimer’s disease

AU - Chen, Sheng

AU - Zhou, Qinming

AU - Ni, You

AU - Le, Weidong

PY - 2020

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N2 - Alzheimer’s disease (AD) is the most common type of dementia and is characterized by progressive cognitive decline. Increasing evidence has demonstrated that the autophagic process plays an important role in AD. In this chapter, we will discuss the role of autophagy in the pathogenesis of AD and other types of dementia, including dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), vascular dementia (VD) and prion diseases. In addition, we will discuss autophagy-targeted therapies as future treatments for AD.

AB - Alzheimer’s disease (AD) is the most common type of dementia and is characterized by progressive cognitive decline. Increasing evidence has demonstrated that the autophagic process plays an important role in AD. In this chapter, we will discuss the role of autophagy in the pathogenesis of AD and other types of dementia, including dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), vascular dementia (VD) and prion diseases. In addition, we will discuss autophagy-targeted therapies as future treatments for AD.

KW - Alzheimer’s disease

KW - Autophagy

KW - Dementia

KW - Frontotemporal Dementia

KW - Humans

KW - Dementia, Vascular

KW - Lewy Body Disease

KW - Alzheimer Disease

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AN - SCOPUS:85088157532

VL - 1207

T3 - Advances in experimental medicine and biology

SP - 3

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BT - Advances in Experimental Medicine and Biology

PB - Springer

ER -

Autophagy and alzheimer’s disease

Abstract

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Keywords

ASJC Scopus subject areas

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