Bacterial characteristics as predictors of posttherapy recurrent bacteriuria among children with acute uncomplicated cystitis caused by Escherichia coli

James R. Johnson; Brian Johnston; Andrew Murray; Michael A. Kuskowski; Joel N. Maslow; Candice Johnson

doi:10.1097/INF.0b013e31814614de

Bacterial characteristics as predictors of posttherapy recurrent bacteriuria among children with acute uncomplicated cystitis caused by Escherichia coli

James R. Johnson, Brian Johnston, Andrew Murray, Michael A. Kuskowski, Joel N. Maslow, Candice Johnson

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Multiple characteristics of pretherapy Escherichia coli urine isolates from 39 children with acute, uncomplicated cystitis (including specific virulence genes and phylogenetic groups) identified an increased risk for recurrent bacteriuria after 3-day (but not 10-day) therapy with amoxicillin-clavulanate. Rapid testing conceivably could facilitate rational selection of treatment duration for pediatric cystitis. Certain traits might represent good targets for preventive interventions.

Original language	English (US)
Pages (from-to)	1151-1153
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	26
Issue number	12
DOIs	https://doi.org/10.1097/INF.0b013e31814614de
State	Published - Dec 2007

Keywords

Escherichia coli infections
Phylogenetics
Polymerase chain reaction
Urinary tract infection
Virulence

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

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10.1097/INF.0b013e31814614de

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title = "Bacterial characteristics as predictors of posttherapy recurrent bacteriuria among children with acute uncomplicated cystitis caused by Escherichia coli",

abstract = "Multiple characteristics of pretherapy Escherichia coli urine isolates from 39 children with acute, uncomplicated cystitis (including specific virulence genes and phylogenetic groups) identified an increased risk for recurrent bacteriuria after 3-day (but not 10-day) therapy with amoxicillin-clavulanate. Rapid testing conceivably could facilitate rational selection of treatment duration for pediatric cystitis. Certain traits might represent good targets for preventive interventions.",

keywords = "Escherichia coli infections, Phylogenetics, Polymerase chain reaction, Urinary tract infection, Virulence",

author = "Johnson, {James R.} and Brian Johnston and Andrew Murray and Kuskowski, {Michael A.} and Maslow, {Joel N.} and Candice Johnson",

note = "Funding Information: Supported by Office of Research and Development, Medical Research Service, Department of Veterans Affairs (to J. R. J. and J. N. M.), and by grants from the National Institutes of Health (to J. R. J.). ",

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AU - Johnston, Brian

AU - Murray, Andrew

AU - Kuskowski, Michael A.

AU - Maslow, Joel N.

AU - Johnson, Candice

N1 - Funding Information: Supported by Office of Research and Development, Medical Research Service, Department of Veterans Affairs (to J. R. J. and J. N. M.), and by grants from the National Institutes of Health (to J. R. J.).

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N2 - Multiple characteristics of pretherapy Escherichia coli urine isolates from 39 children with acute, uncomplicated cystitis (including specific virulence genes and phylogenetic groups) identified an increased risk for recurrent bacteriuria after 3-day (but not 10-day) therapy with amoxicillin-clavulanate. Rapid testing conceivably could facilitate rational selection of treatment duration for pediatric cystitis. Certain traits might represent good targets for preventive interventions.

AB - Multiple characteristics of pretherapy Escherichia coli urine isolates from 39 children with acute, uncomplicated cystitis (including specific virulence genes and phylogenetic groups) identified an increased risk for recurrent bacteriuria after 3-day (but not 10-day) therapy with amoxicillin-clavulanate. Rapid testing conceivably could facilitate rational selection of treatment duration for pediatric cystitis. Certain traits might represent good targets for preventive interventions.

KW - Escherichia coli infections

KW - Phylogenetics

KW - Polymerase chain reaction

KW - Urinary tract infection

KW - Virulence

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Bacterial characteristics as predictors of posttherapy recurrent bacteriuria among children with acute uncomplicated cystitis caused by Escherichia coli

Abstract

Keywords

ASJC Scopus subject areas

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