Abstract
Purpose: To report a case of bilateral herpetic epithelial keratitis after bilateral intravitreal bevacizumab injections for the treatment of exudative age-related macular degeneration. Methods: A 66-year-old man with diabetes and an extensive history of bilateral anti-vascular endothelial growth factor treatments for exudative age-related macular degeneration received an intravitreal bevacizumab injection in the right eye and triple therapy (bevacizumab, photodynamic therapy, and triamcinolone acetonide) in the left eye. After 4 days, he presented with pain, photophobia, tearing, and decreased vision in both eyes. Slit-lamp examination revealed bilateral dendritic epithelial lesions with terminal bulbs, and he was diagnosed with bilateral herpes simplex epithelial keratitis. Results: The patient was treated with ganciclovir ophthalmic ointment and oral acyclovir with resolution of signs and symptoms. Conclusions: To our knowledge, this is the first documented account of bilateral herpetic epithelial keratitis after bilateral intravitreal bevacizumab injections.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 878-879 |
| Number of pages | 2 |
| Journal | Cornea |
| Volume | 36 |
| Issue number | 7 |
| DOIs | |
| State | Published - 2017 |
Keywords
- Age-related macular degeneration
- Bevacizumab
- Diabetes mellitus
- Herpes simplex epithelial keratitis
- Intravitreal injection
ASJC Scopus subject areas
- Ophthalmology