@inbook{df1c73569e484146baf86e3789c0d787,
title = "Bone tissue engineering challenges in oral & Maxillofacial surgery",
abstract = "Over the past decades, there has been a substantial amount of innovation and research into tissue engineering and regenerative approaches for the craniofacial region. This highly complex area presents many unique challenges for tissue engineers. Recent research indicates that various forms of implantable biodegradable scaffolds may play a beneficial role in the clinical treatment of craniofacial pathological conditions. Additionally, the direct delivery of bioactive molecules may further increase de novo bone formation. While these strategies offer an exciting glimpse into potential future treatments, there are several challenges that still must be overcome. In this chapter, we will highlight both current surgical approaches for craniofacial reconstruction and recent advances within the field of bone tissue engineering. The clinical challenges and limitations of these strategies will help contextualize and inform future craniofacial tissue engineering strategies.",
keywords = "Bone regeneration, Bone scaffolds, Growth factor, Maxilofacial reconstruction, Stem cells, Tissue engineering",
author = "Smith, {Brandon T.} and Jonathan Shum and Mark Wong and Mikos, {Antonios G.} and Simon Young",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015.",
year = "2015",
doi = "10.1007/978-3-319-22345-2_4",
language = "English (US)",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York",
pages = "57--78",
booktitle = "Advances in Experimental Medicine and Biology",
address = "United States",
}