Candida auris invasive infections during a COVID-19 case surge

Blake M. Hanson; An Q. Dinh; Truc T. Tran; Sebastian Arenas; Darryl Pronty; Hayley B. Gershengorn; Tanira Ferreira; Cesar A. Arias; Bhavarth S. Shukla

doi:10.1128/AAC.01146-21

Candida auris invasive infections during a COVID-19 case surge

Blake M. Hanson, An Q. Dinh, Truc T. Tran, Sebastian Arenas, Darryl Pronty, Hayley B. Gershengorn, Tanira Ferreira, Cesar A. Arias, Bhavarth S. Shukla

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

Clinical cases of C. auris noted during a COVID-19 surge led to an epidemiological, clinical, and genomic investigation. Evaluation identified a close genetic relationship but inconclusive epidemiologic link between all cases. Prolonged hospitalization due to critical illness from COVID-19 and use of antimicrobials may have contributed to clinical infections.

Original language	English (US)
Article number	e01146-21
Pages (from-to)	e0114621
Journal	Antimicrobial Agents and Chemotherapy
Volume	65
Issue number	10
DOIs	https://doi.org/10.1128/AAC.01146-21
State	Published - Sep 17 2021

Keywords

COVID-19
Candida auris
Outbreak investigation
Whole-genome sequencing
SARS-CoV-2
Candidiasis, Invasive/drug therapy
Humans
Antifungal Agents/therapeutic use
Candida/genetics

ASJC Scopus subject areas

Pharmacology (medical)
Infectious Diseases
Pharmacology

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10.1128/AAC.01146-21

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title = "Candida auris invasive infections during a COVID-19 case surge",

abstract = "Clinical cases of C. auris noted during a COVID-19 surge led to an epidemiological, clinical, and genomic investigation. Evaluation identified a close genetic relationship but inconclusive epidemiologic link between all cases. Prolonged hospitalization due to critical illness from COVID-19 and use of antimicrobials may have contributed to clinical infections.",

keywords = "COVID-19, Candida auris, Outbreak investigation, Whole-genome sequencing, SARS-CoV-2, Candidiasis, Invasive/drug therapy, Humans, Antifungal Agents/therapeutic use, Candida/genetics",

author = "Hanson, {Blake M.} and Dinh, {An Q.} and Tran, {Truc T.} and Sebastian Arenas and Darryl Pronty and Gershengorn, {Hayley B.} and Tanira Ferreira and Arias, {Cesar A.} and Shukla, {Bhavarth S.}",

note = "Funding Information: This study was supported by the National Institute of Allergy and Infectious Diseases at the National Institutes of Health (K01AI148593 and P01AI152999 to B.M.H. and K24AI121296, R01AI134637, R01AI48342, and P01AI152999 to C.A.A.) and a University of Texas STARS Award to C.A.A. Publisher Copyright: Copyright {\textcopyright} 2021 American Society for Microbiology. All Rights Reserved.",

year = "2021",

month = sep,

day = "17",

doi = "10.1128/AAC.01146-21",

language = "English (US)",

volume = "65",

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T1 - Candida auris invasive infections during a COVID-19 case surge

AU - Hanson, Blake M.

AU - Dinh, An Q.

AU - Tran, Truc T.

AU - Arenas, Sebastian

AU - Pronty, Darryl

AU - Gershengorn, Hayley B.

AU - Ferreira, Tanira

AU - Arias, Cesar A.

AU - Shukla, Bhavarth S.

N1 - Funding Information: This study was supported by the National Institute of Allergy and Infectious Diseases at the National Institutes of Health (K01AI148593 and P01AI152999 to B.M.H. and K24AI121296, R01AI134637, R01AI48342, and P01AI152999 to C.A.A.) and a University of Texas STARS Award to C.A.A. Publisher Copyright: Copyright © 2021 American Society for Microbiology. All Rights Reserved.

PY - 2021/9/17

Y1 - 2021/9/17

N2 - Clinical cases of C. auris noted during a COVID-19 surge led to an epidemiological, clinical, and genomic investigation. Evaluation identified a close genetic relationship but inconclusive epidemiologic link between all cases. Prolonged hospitalization due to critical illness from COVID-19 and use of antimicrobials may have contributed to clinical infections.

AB - Clinical cases of C. auris noted during a COVID-19 surge led to an epidemiological, clinical, and genomic investigation. Evaluation identified a close genetic relationship but inconclusive epidemiologic link between all cases. Prolonged hospitalization due to critical illness from COVID-19 and use of antimicrobials may have contributed to clinical infections.

KW - COVID-19

KW - Candida auris

KW - Outbreak investigation

KW - Whole-genome sequencing

KW - SARS-CoV-2

KW - Candidiasis, Invasive/drug therapy

KW - Humans

KW - Antifungal Agents/therapeutic use

KW - Candida/genetics

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JF - Antimicrobial Agents and Chemotherapy

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ER -

Candida auris invasive infections during a COVID-19 case surge

Abstract

Keywords

ASJC Scopus subject areas

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