TY - JOUR
T1 - Cardiac Graft Versus Host Disease
T2 - A Rare or Underrecognized Pathology?
AU - Shrikhande, Bhushan
AU - Khosla, Jagjit
AU - Al-Kindi, Sadeer
AU - Asad, Zain Ul Abideen
AU - Al-Juhaishi, Taha
N1 - Publisher Copyright:
© 2023
PY - 2023/11
Y1 - 2023/11
N2 - Allogeneic hematopoietic stem cell transplantation is a potentially curative procedure for a variety of hematologic and immunologic disorders. Despite the powerful therapeutic potential, both acute, and chronic toxicities including graft versus host disease (GVHD) and cardiovascular disease can lead to significant short- and long-term morbidity and mortality. While GVHD can affect any organ, cardiac involvement is rarely described in the literature. In this review, we review available literature, and allude to pathophysiology and therapeutic approaches in cardiac GVHD.
AB - Allogeneic hematopoietic stem cell transplantation is a potentially curative procedure for a variety of hematologic and immunologic disorders. Despite the powerful therapeutic potential, both acute, and chronic toxicities including graft versus host disease (GVHD) and cardiovascular disease can lead to significant short- and long-term morbidity and mortality. While GVHD can affect any organ, cardiac involvement is rarely described in the literature. In this review, we review available literature, and allude to pathophysiology and therapeutic approaches in cardiac GVHD.
UR - http://www.scopus.com/inward/record.url?scp=85165059491&partnerID=8YFLogxK
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U2 - 10.1016/j.cpcardiol.2023.101807
DO - 10.1016/j.cpcardiol.2023.101807
M3 - Review article
C2 - 37244510
AN - SCOPUS:85165059491
SN - 0146-2806
VL - 48
JO - Current Problems in Cardiology
JF - Current Problems in Cardiology
IS - 11
M1 - 101807
ER -