Cardiovascular Disease in Acromegaly

Morali D Sharma; Anh V Nguyen; Spandana Brown; Richard J Robbins

doi:10.14797/mdcj-13-2-64

Cardiovascular Disease in Acromegaly

Morali D Sharma, Anh V Nguyen, Spandana Brown, Richard J Robbins

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and congestive heart failure. Surgical and/or pharmacological treatment of acromegaly and control of cardiovascular risk factors help reverse some of these pathophysiologic changes and decrease the high risk of cardiovascular complications.

Original language	English (US)
Pages (from-to)	64-67
Number of pages	4
Journal	Methodist DeBakey cardiovascular journal
Volume	13
Issue number	2
DOIs	https://doi.org/10.14797/mdcj-13-2-64
State	Published - Jul 26 2017

Keywords

Journal Article

Access to Document

10.14797/mdcj-13-2-64

Cite this

@article{499f233214cf4a6cb64283d4aa51f1e3,

title = "Cardiovascular Disease in Acromegaly",

abstract = "In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and congestive heart failure. Surgical and/or pharmacological treatment of acromegaly and control of cardiovascular risk factors help reverse some of these pathophysiologic changes and decrease the high risk of cardiovascular complications.",

keywords = "Journal Article",

author = "Sharma, {Morali D} and Nguyen, {Anh V} and Spandana Brown and Robbins, {Richard J}",

year = "2017",

month = jul,

day = "26",

doi = "10.14797/mdcj-13-2-64",

language = "English (US)",

volume = "13",

pages = "64--67",

journal = "Methodist DeBakey cardiovascular journal",

issn = "1947-6094",

publisher = "Methodist DeBakey Heart & Vascular Center",

number = "2",

}

TY - JOUR

T1 - Cardiovascular Disease in Acromegaly

AU - Sharma, Morali D

AU - Nguyen, Anh V

AU - Brown, Spandana

AU - Robbins, Richard J

PY - 2017/7/26

Y1 - 2017/7/26

N2 - In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and congestive heart failure. Surgical and/or pharmacological treatment of acromegaly and control of cardiovascular risk factors help reverse some of these pathophysiologic changes and decrease the high risk of cardiovascular complications.

AB - In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and congestive heart failure. Surgical and/or pharmacological treatment of acromegaly and control of cardiovascular risk factors help reverse some of these pathophysiologic changes and decrease the high risk of cardiovascular complications.

KW - Journal Article

U2 - 10.14797/mdcj-13-2-64

DO - 10.14797/mdcj-13-2-64

M3 - Article

C2 - 28740584

SN - 1947-6094

VL - 13

SP - 64

EP - 67

JO - Methodist DeBakey cardiovascular journal

JF - Methodist DeBakey cardiovascular journal

IS - 2

ER -

Cardiovascular Disease in Acromegaly

Abstract

Keywords

Access to Document

Fingerprint

Cite this