Case of recurrent superficial CD34-positive fibroblastic tumor

Haneen T. Salah; Julieta A. D'Ardis; Donghwa Baek; Juanita Duran; Mary R. Schwartz; Alberto G. Ayala; Jae Y. Ro

doi:10.1111/cup.14329

Case of recurrent superficial CD34-positive fibroblastic tumor

Haneen T. Salah, Julieta A. D'Ardis, Donghwa Baek, Juanita Duran, Mary R. Schwartz, Alberto G. Ayala, Jae Y. Ro

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described rare superficial mesenchymal tumor. SCPFT has a distinctive morphologic appearance, marked by significant nuclear pleomorphism, low mitotic rate, and diffuse CD34 positivity. SCPFT is underdiagnosed because of its rarity and misdiagnosis as sarcoma, with very few reported cases of local recurrence or metastasis. Recognition and awareness of SCPFT are essential for accurate diagnosis and appropriate clinical management. We describe here the case of a 37-year-old male who presented with a right calf mass diagnosed as SCPFT with subsequent local recurrence of the tumor.

Original language	English (US)
Pages (from-to)	477-480
Number of pages	4
Journal	Journal of Cutaneous Pathology
Volume	50
Issue number	6
DOIs	https://doi.org/10.1111/cup.14329
State	Published - Jun 2023

Keywords

CD34 positive
SCPFT
fibroblastic tumor
recurrence
Antigens, CD34
Immunohistochemistry
Neoplasms, Fibrous Tissue/diagnosis
Humans
Soft Tissue Neoplasms/pathology
Male
Adult
Biomarkers, Tumor

ASJC Scopus subject areas

Dermatology
Pathology and Forensic Medicine
Histology

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10.1111/cup.14329

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title = "Case of recurrent superficial CD34-positive fibroblastic tumor",

abstract = "Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described rare superficial mesenchymal tumor. SCPFT has a distinctive morphologic appearance, marked by significant nuclear pleomorphism, low mitotic rate, and diffuse CD34 positivity. SCPFT is underdiagnosed because of its rarity and misdiagnosis as sarcoma, with very few reported cases of local recurrence or metastasis. Recognition and awareness of SCPFT are essential for accurate diagnosis and appropriate clinical management. We describe here the case of a 37-year-old male who presented with a right calf mass diagnosed as SCPFT with subsequent local recurrence of the tumor.",

keywords = "CD34 positive, SCPFT, fibroblastic tumor, recurrence, Antigens, CD34, Immunohistochemistry, Neoplasms, Fibrous Tissue/diagnosis, Humans, Soft Tissue Neoplasms/pathology, Male, Adult, Biomarkers, Tumor",

author = "Salah, {Haneen T.} and D'Ardis, {Julieta A.} and Donghwa Baek and Juanita Duran and Schwartz, {Mary R.} and Ayala, {Alberto G.} and Ro, {Jae Y.}",

note = "{\textcopyright} 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",

year = "2023",

month = jun,

doi = "10.1111/cup.14329",

language = "English (US)",

volume = "50",

pages = "477--480",

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AU - Salah, Haneen T.

AU - D'Ardis, Julieta A.

AU - Baek, Donghwa

AU - Duran, Juanita

AU - Schwartz, Mary R.

AU - Ayala, Alberto G.

AU - Ro, Jae Y.

PY - 2023/6

Y1 - 2023/6

N2 - Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described rare superficial mesenchymal tumor. SCPFT has a distinctive morphologic appearance, marked by significant nuclear pleomorphism, low mitotic rate, and diffuse CD34 positivity. SCPFT is underdiagnosed because of its rarity and misdiagnosis as sarcoma, with very few reported cases of local recurrence or metastasis. Recognition and awareness of SCPFT are essential for accurate diagnosis and appropriate clinical management. We describe here the case of a 37-year-old male who presented with a right calf mass diagnosed as SCPFT with subsequent local recurrence of the tumor.

AB - Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described rare superficial mesenchymal tumor. SCPFT has a distinctive morphologic appearance, marked by significant nuclear pleomorphism, low mitotic rate, and diffuse CD34 positivity. SCPFT is underdiagnosed because of its rarity and misdiagnosis as sarcoma, with very few reported cases of local recurrence or metastasis. Recognition and awareness of SCPFT are essential for accurate diagnosis and appropriate clinical management. We describe here the case of a 37-year-old male who presented with a right calf mass diagnosed as SCPFT with subsequent local recurrence of the tumor.

KW - CD34 positive

KW - SCPFT

KW - fibroblastic tumor

KW - recurrence

KW - Antigens, CD34

KW - Immunohistochemistry

KW - Neoplasms, Fibrous Tissue/diagnosis

KW - Humans

KW - Soft Tissue Neoplasms/pathology

KW - Male

KW - Adult

KW - Biomarkers, Tumor

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JO - Journal of Cutaneous Pathology

JF - Journal of Cutaneous Pathology

IS - 6

ER -

Case of recurrent superficial CD34-positive fibroblastic tumor

Abstract

Keywords

ASJC Scopus subject areas

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