CD28: Beyond just T-cell costimulation

Xian C. Li; Mohamed H. Sayegh

doi:10.1182/blood-2007-01-067330

CD28: Beyond just T-cell costimulation

Xian C. Li, Mohamed H. Sayegh

Research output: Contribution to journal › Review article › peer-review

Abstract

The CD28T-cell costimulatory molecule was shown to regulate in vivo migration of memory T cells independent of TCR stimulation, suggesting that CD28 can have additional functions beyond costimulation. However, the mechanism involved, the physiological relevance, and the therapeutic implications await further investigation.

Original language	English (US)
Pages (from-to)	2668-2669
Number of pages	2
Journal	Blood
Volume	109
Issue number	7
DOIs	https://doi.org/10.1182/blood-2007-01-067330
State	Published - Apr 1 2007

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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10.1182/blood-2007-01-067330

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title = "CD28: Beyond just T-cell costimulation",

abstract = "The CD28T-cell costimulatory molecule was shown to regulate in vivo migration of memory T cells independent of TCR stimulation, suggesting that CD28 can have additional functions beyond costimulation. However, the mechanism involved, the physiological relevance, and the therapeutic implications await further investigation.",

author = "Li, {Xian C.} and Sayegh, {Mohamed H.}",

year = "2007",

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AU - Sayegh, Mohamed H.

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AB - The CD28T-cell costimulatory molecule was shown to regulate in vivo migration of memory T cells independent of TCR stimulation, suggesting that CD28 can have additional functions beyond costimulation. However, the mechanism involved, the physiological relevance, and the therapeutic implications await further investigation.

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JO - Blood

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CD28: Beyond just T-cell costimulation

Abstract

ASJC Scopus subject areas

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