@inbook{efd0013e55584d2092ccbaa709b441e1,
title = "Cell biology at the interface of nanobiosensors and microfluidics",
abstract = "It is at the nanometer scale where biology, chemistry, and material science converge. With recent progresses in nanotechnology, research in cell biology has gained enormous interest from a growing multidisciplinary community of scientists in academia and industry. Many efforts have been made to discover cures for diseases through advancements in nanobiosensors and microfluidics. In this chapter, we give a general introduction to nanobiosensors and microfluidics technology, present key developments in the field, and illustrate the breadth of microfluidics-based sensing strategies available for cell biology. We also provide protocols for fabricating localized surface plasmon resonance (LSPR)-based nanobiosensors, and for integration of LSPR with a microfluidic device. Finally, we highlight applications and challenges associated with the use of nanobiosensing and microfluidics technology. This chapter should provide a solid platform for cell biologists to develop simple microfluidic LSPR chips for routine cell-based assays.",
keywords = "Bioassays, Biosensors, Cell biology, LSPR, Microfluidics, Nanoplasmonics",
author = "Nikhil Bhalla and Chiang, {Hung Ju} and Shen, {Amy Q.}",
note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",
year = "2018",
doi = "10.1016/bs.mcb.2018.09.009",
language = "English (US)",
isbn = "9780128142844",
series = "Methods in Cell Biology",
publisher = "Academic Press",
pages = "203--227",
editor = "Fletcher, {Daniel A.} and Junsang Doh and Matthieu Piel",
booktitle = "Microfluidics in Cell Biology Part C",
address = "United States",
}