Abstract
We recorded neurons in rat cerebral cortex with activity relating to the neurogenic elevations in regional cerebral blood flow (rCBF) coupled to stereotyped bursts of EEG activity, burst-cerebrovascular wave complexes, appearing spontaneously or evoked by electrical stimulation of rostral ventrolateral medulla (RVL) or fastigial nucleus (FN). Of 333 spontaneously active neurons only 15 (5%), in layers 5-6, consistently (P < 0.05, chi-square) increased their activity during the earliest potential of the complex, ~1.3 s before the rise of rCBF, and during the minutes-long elevation of rCBF elicited by 10 s of stimulation of RVL or FN. The results indicate the presence of a small population of neurons in deep cortical laminae whose activity correlates with neurogenic elevations of rCBF. These neurons may function to transduce afferent neuronal signals into vasodilation.
Original language | English (US) |
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Pages (from-to) | 101-104 |
Number of pages | 4 |
Journal | Neuroscience Letters |
Volume | 209 |
Issue number | 2 |
DOIs | |
State | Published - May 10 1996 |
Keywords
- Cerebral cortex
- EEG
- Electrical stimulation
- Fastigial nucleus
- Neurons
- Regional cerebral blood flow
- Rostral ventrolateral medulla
- Vasodilation
ASJC Scopus subject areas
- Neuroscience(all)