Consensus on β-Lactamase Nomenclature

Patricia A. Bradford; Robert A. Bonomo; Karen Bush; Alessandra Carattoli; Michael Feldgarden; Daniel H. Haft; Yoshikazu Ishii; George A. Jacoby; William Klimke; Timothy Palzkill; Laurent Poirel; Gian Maria Rossolini; Pranita D. Tamma; Cesar A. Arias

doi:10.1128/aac.00333-22

Consensus on β-Lactamase Nomenclature

Patricia A. Bradford, Robert A. Bonomo, Karen Bush, Alessandra Carattoli, Michael Feldgarden, Daniel H. Haft, Yoshikazu Ishii, George A. Jacoby, William Klimke, Timothy Palzkill, Laurent Poirel, Gian Maria Rossolini, Pranita D. Tamma, Cesar A. Arias

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

Assigning names to β-lactamase variants has been inconsistent and has led to confusion in the published literature. The common availability of whole genome sequencing has resulted in an exponential growth in the number of new β-lactamase genes. In November 2021 an international group of β-lactamase experts met virtually to develop a consensus for the way naturally-occurring β-lactamase genes should be named. This document formalizes the process for naming novel β-lactamases, followed by their subsequent publication.

Original language	English (US)
Pages (from-to)	e0033322
Journal	Antimicrobial Agents and Chemotherapy
Volume	66
Issue number	4
DOIs	https://doi.org/10.1128/aac.00333-22
State	Published - Apr 19 2022

Keywords

beta-lactamases
beta-Lactamase Inhibitors
beta-Lactamases/genetics
Consensus

ASJC Scopus subject areas

Pharmacology (medical)
Infectious Diseases
Pharmacology

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10.1128/aac.00333-22

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title = "Consensus on β-Lactamase Nomenclature",

abstract = "Assigning names to β-lactamase variants has been inconsistent and has led to confusion in the published literature. The common availability of whole genome sequencing has resulted in an exponential growth in the number of new β-lactamase genes. In November 2021 an international group of β-lactamase experts met virtually to develop a consensus for the way naturally-occurring β-lactamase genes should be named. This document formalizes the process for naming novel β-lactamases, followed by their subsequent publication.",

keywords = "beta-lactamases, beta-Lactamase Inhibitors, beta-Lactamases/genetics, Consensus",

author = "Bradford, {Patricia A.} and Bonomo, {Robert A.} and Karen Bush and Alessandra Carattoli and Michael Feldgarden and Haft, {Daniel H.} and Yoshikazu Ishii and Jacoby, {George A.} and William Klimke and Timothy Palzkill and Laurent Poirel and Rossolini, {Gian Maria} and Tamma, {Pranita D.} and Arias, {Cesar A.}",

note = "Funding Information: This work was supported in part by the National Center for Biotechnology Information of the National Library of Medicine, National Institutes of Health. Publisher Copyright: {\textcopyright} 2022 American Society for Microbiology. All rights reserved.",

year = "2022",

month = apr,

day = "19",

doi = "10.1128/aac.00333-22",

language = "English (US)",

volume = "66",

pages = "e0033322",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

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T1 - Consensus on β-Lactamase Nomenclature

AU - Bradford, Patricia A.

AU - Bonomo, Robert A.

AU - Bush, Karen

AU - Carattoli, Alessandra

AU - Feldgarden, Michael

AU - Haft, Daniel H.

AU - Ishii, Yoshikazu

AU - Jacoby, George A.

AU - Klimke, William

AU - Palzkill, Timothy

AU - Poirel, Laurent

AU - Rossolini, Gian Maria

AU - Tamma, Pranita D.

AU - Arias, Cesar A.

N1 - Funding Information: This work was supported in part by the National Center for Biotechnology Information of the National Library of Medicine, National Institutes of Health. Publisher Copyright: © 2022 American Society for Microbiology. All rights reserved.

PY - 2022/4/19

Y1 - 2022/4/19

N2 - Assigning names to β-lactamase variants has been inconsistent and has led to confusion in the published literature. The common availability of whole genome sequencing has resulted in an exponential growth in the number of new β-lactamase genes. In November 2021 an international group of β-lactamase experts met virtually to develop a consensus for the way naturally-occurring β-lactamase genes should be named. This document formalizes the process for naming novel β-lactamases, followed by their subsequent publication.

AB - Assigning names to β-lactamase variants has been inconsistent and has led to confusion in the published literature. The common availability of whole genome sequencing has resulted in an exponential growth in the number of new β-lactamase genes. In November 2021 an international group of β-lactamase experts met virtually to develop a consensus for the way naturally-occurring β-lactamase genes should be named. This document formalizes the process for naming novel β-lactamases, followed by their subsequent publication.

KW - beta-lactamases

KW - beta-Lactamase Inhibitors

KW - beta-Lactamases/genetics

KW - Consensus

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M3 - Review article

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AN - SCOPUS:85128448945

SN - 0066-4804

VL - 66

SP - e0033322

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 4

ER -

Consensus on β-Lactamase Nomenclature

Abstract

Keywords

ASJC Scopus subject areas

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