La malattia coronarica del cuore trapiantato: Interazione fisiopatologica tra sistema immunitario, infezioni e sindrome metabolica

Luciano Potena; Rossella Ferrara; Edward S. Mocarski; David B. Lewis; John P. Cooke; Francesco Grigioni; Fabio Coccolo; Gaia Magnani; Francesco Fallani; Carlo Magelli; Hannah A. Valantine; Angelo Branzi

La malattia coronarica del cuore trapiantato: Interazione fisiopatologica tra sistema immunitario, infezioni e sindrome metabolica

Translated title of the contribution: Coronary allograft vasculopathy: Pathophysiological interaction between the immune system, infections and metabolic syndrome

Luciano Potena, Rossella Ferrara, Edward S. Mocarski, David B. Lewis, John P. Cooke, Francesco Grigioni, Fabio Coccolo, Gaia Magnani, Francesco Fallani, Carlo Magelli, Hannah A. Valantine, Angelo Branzi

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Cardiac allograft vasculopathy is still the main cause of long-term graft loss after heart transplantation. Indeed, recent advances in immunosuppression management led to a significant improvement in short-term survival, while long-term death rate did not change significantly in the last 20 years. In this paper, we will review the latest advances in the understanding of this peculiar form of atherosclerosis, focusing on the mechanisms that can be potentially targeted by specific therapeutic interventions.

Translated title of the contribution	Coronary allograft vasculopathy: Pathophysiological interaction between the immune system, infections and metabolic syndrome
Original language	Italian
Pages (from-to)	73-82
Number of pages	10
Journal	Giornale Italiano di Cardiologia
Volume	8
Issue number	2
State	Published - Feb 2007

Keywords

Atherosclerosis
Cytomegalovirus
Endothelium
Heart transplantation
Metabolic syndrome
Rejection

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Cite this

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title = "La malattia coronarica del cuore trapiantato: Interazione fisiopatologica tra sistema immunitario, infezioni e sindrome metabolica",

abstract = "Cardiac allograft vasculopathy is still the main cause of long-term graft loss after heart transplantation. Indeed, recent advances in immunosuppression management led to a significant improvement in short-term survival, while long-term death rate did not change significantly in the last 20 years. In this paper, we will review the latest advances in the understanding of this peculiar form of atherosclerosis, focusing on the mechanisms that can be potentially targeted by specific therapeutic interventions.",

keywords = "Atherosclerosis, Cytomegalovirus, Endothelium, Heart transplantation, Metabolic syndrome, Rejection",

author = "Luciano Potena and Rossella Ferrara and Mocarski, {Edward S.} and Lewis, {David B.} and Cooke, {John P.} and Francesco Grigioni and Fabio Coccolo and Gaia Magnani and Francesco Fallani and Carlo Magelli and Valantine, {Hannah A.} and Angelo Branzi",

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language = "Italian",

volume = "8",

pages = "73--82",

journal = "Giornale Italiano di Cardiologia",

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TY - JOUR

T1 - La malattia coronarica del cuore trapiantato

T2 - Interazione fisiopatologica tra sistema immunitario, infezioni e sindrome metabolica

AU - Potena, Luciano

AU - Ferrara, Rossella

AU - Mocarski, Edward S.

AU - Lewis, David B.

AU - Cooke, John P.

AU - Grigioni, Francesco

AU - Coccolo, Fabio

AU - Magnani, Gaia

AU - Fallani, Francesco

AU - Magelli, Carlo

AU - Valantine, Hannah A.

AU - Branzi, Angelo

PY - 2007/2

Y1 - 2007/2

N2 - Cardiac allograft vasculopathy is still the main cause of long-term graft loss after heart transplantation. Indeed, recent advances in immunosuppression management led to a significant improvement in short-term survival, while long-term death rate did not change significantly in the last 20 years. In this paper, we will review the latest advances in the understanding of this peculiar form of atherosclerosis, focusing on the mechanisms that can be potentially targeted by specific therapeutic interventions.

AB - Cardiac allograft vasculopathy is still the main cause of long-term graft loss after heart transplantation. Indeed, recent advances in immunosuppression management led to a significant improvement in short-term survival, while long-term death rate did not change significantly in the last 20 years. In this paper, we will review the latest advances in the understanding of this peculiar form of atherosclerosis, focusing on the mechanisms that can be potentially targeted by specific therapeutic interventions.

KW - Atherosclerosis

KW - Cytomegalovirus

KW - Endothelium

KW - Heart transplantation

KW - Metabolic syndrome

KW - Rejection

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M3 - Review article

C2 - 17402351

AN - SCOPUS:34147208751

SN - 1827-6806

VL - 8

SP - 73

EP - 82

JO - Giornale Italiano di Cardiologia

JF - Giornale Italiano di Cardiologia

IS - 2

ER -

La malattia coronarica del cuore trapiantato: Interazione fisiopatologica tra sistema immunitario, infezioni e sindrome metabolica

Abstract

Keywords

ASJC Scopus subject areas

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