1 Scopus citations

Abstract

Corticosteroids have been utilized as mainstay pharmacological intervention for successful organ transplantation since the beginning. Several challenges exist in establishing a balance between achieving a tolerant atmosphere in the host immune system while minimizing the long-term impact of steroids on the body. Corticosteroids are used early in all solid organ transplantation but there is wide variability across various organs and centers in the duration of use and protocols of planned steroid wean. The adverse event profile of steroids is exhaustive and across many organ systems.

Original languageEnglish (US)
Title of host publicationHandbook of Experimental Pharmacology
PublisherSpringer Science and Business Media Deutschland GmbH
Pages73-84
Number of pages12
Volume272
DOIs
StatePublished - 2022

Publication series

NameHandbook of experimental pharmacology
ISSN (Print)0171-2004

Keywords

  • Immunosuppression
  • Organ transplantation
  • Steroids
  • Immunosuppressive Agents/adverse effects
  • Adrenal Cortex Hormones/therapeutic use
  • Humans
  • Graft Rejection
  • Immunosuppression Therapy

ASJC Scopus subject areas

  • Biochemistry
  • Pharmacology, Toxicology and Pharmaceutics(all)

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