Abstract
Complex biochemical and biophysical barriers inhibit the efficacy of chemotherapy, and the likelihood that chemotherapy will fail as a result of drug resistance in many forms is high. Clearly a more concerted, concentrated, and collaborative effort is required between oncologists, pathologists, chemists, applied mathematicians, and physicists if progress is to be made in the fight against cancer. Physical oncology has the potential to bridge the gap between these disciplines, quantifying through mathematical modeling the biophysical conditions affecting cancer treatment and tumor growth at multiple scales within the body, from the molecular (nano-) scale to the macroscale (whole body systems).
| Original language | English (US) |
|---|---|
| Title of host publication | An Introduction to Physical Oncology |
| Subtitle of host publication | How Mechanistic Mathematical Modeling Can Improve Cancer Therapy Outcomes |
| Publisher | CRC Press |
| Pages | 13-30 |
| Number of pages | 18 |
| ISBN (Electronic) | 9781466551367 |
| ISBN (Print) | 9781466551343 |
| DOIs | |
| State | Published - Jan 1 2017 |
ASJC Scopus subject areas
- Mathematics(all)
- Medicine(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Physics and Astronomy(all)