TY - JOUR
T1 - Drug treatment of hyperlipidemia
AU - Yeshurun, D.
AU - Gotto, A. M.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1976/3
Y1 - 1976/3
N2 - The most frequent indication for treatment of hyperlipidemia is for prevention of arteriosclerosis, a suspected but unproved benefit. The cornerstone of treatment of primary hyperlipidemia is diet; drugs may be added to, but do not replace, diet. When a drug is used with any patient, its potential benefits and hazards must be carefully weighed for the given subject. The subjects should be carefully followed and observed for side effects. Plasma lipids should be monitored during the course of treatment. Five drugs have been approved by the U.S. Food and Drug Administration for the treatment of hyperlipidemia: cholestyramine, clofibrate, nicotinic acid, sodium dextrothyroxine and beta-sitosterol. The use, the actions and the side effects of each and of several nonapproved agents are discussed.
AB - The most frequent indication for treatment of hyperlipidemia is for prevention of arteriosclerosis, a suspected but unproved benefit. The cornerstone of treatment of primary hyperlipidemia is diet; drugs may be added to, but do not replace, diet. When a drug is used with any patient, its potential benefits and hazards must be carefully weighed for the given subject. The subjects should be carefully followed and observed for side effects. Plasma lipids should be monitored during the course of treatment. Five drugs have been approved by the U.S. Food and Drug Administration for the treatment of hyperlipidemia: cholestyramine, clofibrate, nicotinic acid, sodium dextrothyroxine and beta-sitosterol. The use, the actions and the side effects of each and of several nonapproved agents are discussed.
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U2 - 10.1016/0002-9343(76)90755-5
DO - 10.1016/0002-9343(76)90755-5
M3 - Review article
C2 - 1258886
AN - SCOPUS:0017294828
SN - 0002-9343
VL - 60
SP - 379
EP - 396
JO - The American journal of medicine
JF - The American journal of medicine
IS - 3
ER -