Emerging application of stereotactic body radiation therapy for gynecologic malignancies

Nina A. Mayr; Zhibin Huang; Jason W. Sohn; Simon S. Lo; Bin S. Teh; Jiade J. Lu; John C. Grecula; Charles Kunos

doi:10.1586/era.11.81

Emerging application of stereotactic body radiation therapy for gynecologic malignancies

Nina A. Mayr, Zhibin Huang, Jason W. Sohn, Simon S. Lo, Bin S. Teh, Jiade J. Lu, John C. Grecula, Charles Kunos

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Stereotactic body radiation therapy (SBRT) involves delivery of image-guided, ablative radiation doses to planning treatment volume(s) using sophisticated dosimetric planning and target localization. Early on, clinical investigators pursued SBRT for the treatment of early stage non-small-cell lung cancer, lung and liver oligometastases and spinal metastases. As a result of its clinical efficacy in these disease sites, SBRT has been explored in the management of persistent or recurrent gynecological cancers. This article will consider indications for SBRT application in gynecological cancer management, will reflect on outcomes from key SBRT clinical trials and will discuss new therapeutic roles of SBRT for gynecological cancers.

Original language	English (US)
Pages (from-to)	1071-1077
Number of pages	7
Journal	Expert Review of Anticancer Therapy
Volume	11
Issue number	7
DOIs	https://doi.org/10.1586/era.11.81
State	Published - Jul 2011

Keywords

gynecologic malignancies
radiation therapy
stereotactic

ASJC Scopus subject areas

Pharmacology (medical)
Oncology

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10.1586/era.11.81

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abstract = "Stereotactic body radiation therapy (SBRT) involves delivery of image-guided, ablative radiation doses to planning treatment volume(s) using sophisticated dosimetric planning and target localization. Early on, clinical investigators pursued SBRT for the treatment of early stage non-small-cell lung cancer, lung and liver oligometastases and spinal metastases. As a result of its clinical efficacy in these disease sites, SBRT has been explored in the management of persistent or recurrent gynecological cancers. This article will consider indications for SBRT application in gynecological cancer management, will reflect on outcomes from key SBRT clinical trials and will discuss new therapeutic roles of SBRT for gynecological cancers.",

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AU - Lo, Simon S.

AU - Teh, Bin S.

AU - Lu, Jiade J.

AU - Grecula, John C.

AU - Kunos, Charles

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AB - Stereotactic body radiation therapy (SBRT) involves delivery of image-guided, ablative radiation doses to planning treatment volume(s) using sophisticated dosimetric planning and target localization. Early on, clinical investigators pursued SBRT for the treatment of early stage non-small-cell lung cancer, lung and liver oligometastases and spinal metastases. As a result of its clinical efficacy in these disease sites, SBRT has been explored in the management of persistent or recurrent gynecological cancers. This article will consider indications for SBRT application in gynecological cancer management, will reflect on outcomes from key SBRT clinical trials and will discuss new therapeutic roles of SBRT for gynecological cancers.

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Emerging application of stereotactic body radiation therapy for gynecologic malignancies

Abstract

Keywords

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