TY - GEN
T1 - Engineering the abio-bio interface to enable more than moore in functional bioelectronics
AU - Guiseppi-Elie, A.
AU - Kotanen, C.
AU - Karunwi, O.
AU - Wilson, A. N.
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - The need for biocompatible, low impedance abio-to-bio interfaces suitable for implantable bioactive devices has led us to develop electroconductive hydrogels. Conductive electroactive polymers (CEPs) are one dimensional organic semiconductors synthesized from aromatic monomers into extended pi-conjugated polymers. The synthesis of CEPs in association with hydrogels produces class of hybrid materials with the conductivity of the CEP and inherent biocompatibility of the hydrogel. CEPs provide a means for the additive electrodeposition of biorecognition molecules to specific nano- and micron-dimensioned metallic and semiconducting sites on microfabricated metallic or semiconductor MEMS devices. Through judicious engineering of repeat unit chemistry, polymer architecture, crosslink density and microstructure, the mechanical, transport and surface properties may be controlled. Implanted, these materials enable programmed low voltage electro-release of factors suitable for mitigating inflammatory response. Finally, these hydrogels can accommodate supramolecular assemblies of CNTs and enzymes supporting direct electron transfer for generation-3 biosensors and implantable biofuel cells.
AB - The need for biocompatible, low impedance abio-to-bio interfaces suitable for implantable bioactive devices has led us to develop electroconductive hydrogels. Conductive electroactive polymers (CEPs) are one dimensional organic semiconductors synthesized from aromatic monomers into extended pi-conjugated polymers. The synthesis of CEPs in association with hydrogels produces class of hybrid materials with the conductivity of the CEP and inherent biocompatibility of the hydrogel. CEPs provide a means for the additive electrodeposition of biorecognition molecules to specific nano- and micron-dimensioned metallic and semiconducting sites on microfabricated metallic or semiconductor MEMS devices. Through judicious engineering of repeat unit chemistry, polymer architecture, crosslink density and microstructure, the mechanical, transport and surface properties may be controlled. Implanted, these materials enable programmed low voltage electro-release of factors suitable for mitigating inflammatory response. Finally, these hydrogels can accommodate supramolecular assemblies of CNTs and enzymes supporting direct electron transfer for generation-3 biosensors and implantable biofuel cells.
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U2 - 10.1149/05014.0013ecst
DO - 10.1149/05014.0013ecst
M3 - Conference contribution
AN - SCOPUS:84885763916
SN - 9781623320133
T3 - ECS Transactions
SP - 13
EP - 29
BT - International Symposium on Functional Diversification of Semiconductor Electronics
PB - Electrochemical Society Inc.
T2 - Symposium on More than Moore - 222nd ECS Meeting/PRiME 2012
Y2 - 7 October 2012 through 12 October 2012
ER -