Epithelioid cutaneous mesenchymal neoplasms: A practical diagnostic approach

Joon Hyuk Choi; Jae Y. Ro

doi:10.3390/diagnostics10040233

Epithelioid cutaneous mesenchymal neoplasms: A practical diagnostic approach

Joon Hyuk Choi, Jae Y. Ro

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Epithelioid cells are rounded or polygonal cells with abundant eosinophilic or clear cytoplasm and ovoid to round nuclei, superficially resembling epithelial cells. Cutaneous mesenchymal neoplasms composed predominantly or exclusively of epithelioid cells are relatively uncommon and can cause considerable diagnostic difficulties due to overlapping histologic features among heterogeneous groups of tumors. Familiaritywith practical diagnostic approaches and recognition of key histopathologic features are important for correct diagnosis and management. This review summarizes the histologic features of epithelioid cutaneous mesenchymal neoplasms and discusses their differential diagnoses from malignant melanomas and carcinomas.

Original language	English (US)
Article number	233
Journal	Diagnostics
Volume	10
Issue number	4
DOIs	https://doi.org/10.3390/diagnostics10040233
State	Published - Apr 17 2020

Keywords

Carcinoma
Diagnosis
Epithelioid cells
Melanoma
Sarcoma
Skin neoplasms

ASJC Scopus subject areas

Clinical Biochemistry

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10.3390/diagnostics10040233

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@article{0b1e16a6506c4c9c860467222e49baed,

title = "Epithelioid cutaneous mesenchymal neoplasms: A practical diagnostic approach",

abstract = "Epithelioid cells are rounded or polygonal cells with abundant eosinophilic or clear cytoplasm and ovoid to round nuclei, superficially resembling epithelial cells. Cutaneous mesenchymal neoplasms composed predominantly or exclusively of epithelioid cells are relatively uncommon and can cause considerable diagnostic difficulties due to overlapping histologic features among heterogeneous groups of tumors. Familiaritywith practical diagnostic approaches and recognition of key histopathologic features are important for correct diagnosis and management. This review summarizes the histologic features of epithelioid cutaneous mesenchymal neoplasms and discusses their differential diagnoses from malignant melanomas and carcinomas.",

keywords = "Carcinoma, Diagnosis, Epithelioid cells, Melanoma, Sarcoma, Skin neoplasms",

author = "Choi, {Joon Hyuk} and Ro, {Jae Y.}",

note = "Funding Information: Funding: This work was supported by the 2018 Yeungnam University Research Grant. Publisher Copyright: {\textcopyright} 2020 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2020",

month = apr,

day = "17",

doi = "10.3390/diagnostics10040233",

language = "English (US)",

volume = "10",

journal = "Diagnostics",

issn = "2075-4418",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

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TY - JOUR

T1 - Epithelioid cutaneous mesenchymal neoplasms

T2 - A practical diagnostic approach

AU - Choi, Joon Hyuk

AU - Ro, Jae Y.

PY - 2020/4/17

Y1 - 2020/4/17

N2 - Epithelioid cells are rounded or polygonal cells with abundant eosinophilic or clear cytoplasm and ovoid to round nuclei, superficially resembling epithelial cells. Cutaneous mesenchymal neoplasms composed predominantly or exclusively of epithelioid cells are relatively uncommon and can cause considerable diagnostic difficulties due to overlapping histologic features among heterogeneous groups of tumors. Familiaritywith practical diagnostic approaches and recognition of key histopathologic features are important for correct diagnosis and management. This review summarizes the histologic features of epithelioid cutaneous mesenchymal neoplasms and discusses their differential diagnoses from malignant melanomas and carcinomas.

AB - Epithelioid cells are rounded or polygonal cells with abundant eosinophilic or clear cytoplasm and ovoid to round nuclei, superficially resembling epithelial cells. Cutaneous mesenchymal neoplasms composed predominantly or exclusively of epithelioid cells are relatively uncommon and can cause considerable diagnostic difficulties due to overlapping histologic features among heterogeneous groups of tumors. Familiaritywith practical diagnostic approaches and recognition of key histopathologic features are important for correct diagnosis and management. This review summarizes the histologic features of epithelioid cutaneous mesenchymal neoplasms and discusses their differential diagnoses from malignant melanomas and carcinomas.

KW - Carcinoma

KW - Diagnosis

KW - Epithelioid cells

KW - Melanoma

KW - Sarcoma

KW - Skin neoplasms

UR - http://www.scopus.com/inward/record.url?scp=85083772198&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85083772198&partnerID=8YFLogxK

U2 - 10.3390/diagnostics10040233

DO - 10.3390/diagnostics10040233

M3 - Review article

C2 - 32316685

AN - SCOPUS:85083772198

SN - 2075-4418

VL - 10

JO - Diagnostics

JF - Diagnostics

IS - 4

M1 - 233

ER -

Epithelioid cutaneous mesenchymal neoplasms: A practical diagnostic approach

Abstract

Keywords

ASJC Scopus subject areas

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