Erratum: Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246)

Meenakshi Hegde; Malini Mukherjee; Zakaria Grada; Antonella Pignata; Daniel Landi; Shoba A. Navai; Amanda Wakefield; Kristen Fousek; Kevin Bielamowicz; Kevin K.H. Chow; Vita S. Brawley; Tiara T. Byrd; Simone Krebs; Stephen Gottschalk; Winfried S. Wels; Matthew L. Baker; Gianpietro Dotti; Maksim Mamonkin; Malcolm K. Brenner; Jordan S. Orange; Nabil Ahmed

doi:10.1172/JCI131245

Erratum: Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246)

Meenakshi Hegde, Malini Mukherjee, Zakaria Grada, Antonella Pignata, Daniel Landi, Shoba A. Navai, Amanda Wakefield, Kristen Fousek, Kevin Bielamowicz, Kevin K.H. Chow, Vita S. Brawley, Tiara T. Byrd, Simone Krebs, Stephen Gottschalk, Winfried S. Wels, Matthew L. Baker, Gianpietro Dotti, Maksim Mamonkin, Malcolm K. Brenner, Jordan S. OrangeNabil Ahmed

Research output: Contribution to journal › Comment/debate › peer-review

17 Scopus citations

Abstract

A reader recently alerted the Journal that two images in this JCI article appear similar to images subsequently published in a Neuro-Oncology paper from the same lab as unique samples (1). Specifically, in Figure 9D of the JCI paper, the image for IL13Rα2 staining for the HER2 CAR sample appears to be similar to the image for EphA2 staining of a nontransduced T cell–treated sample published in Figure 6A of the Neuro-Oncology paper. In addition, in Figure 9D of the JCI paper, the image for IL13Rα2 staining for the tumor sample appears to be similar to the image for HER2 staining of a nontransduced T cell–treated sample in Figure 6B of the Neuro-Oncology paper. An institutional investigation into this matter is ongoing, and we will inform our readers of the outcome when the investigation is complete.

Original language	English (US)
Pages (from-to)	3464
Number of pages	1
Journal	Journal of Clinical Investigation
Volume	129
Issue number	8
DOIs	https://doi.org/10.1172/JCI131245
State	Published - Aug 1 2019

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Medicine(all)

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Hegde, M., Mukherjee, M., Grada, Z., Pignata, A., Landi, D., Navai, S. A., Wakefield, A., Fousek, K., Bielamowicz, K., Chow, K. K. H., Brawley, V. S., Byrd, T. T., Krebs, S., Gottschalk, S., Wels, W. S., Baker, M. L., Dotti, G., Mamonkin, M., Brenner, M. K., ... Ahmed, N. (2019). Erratum: Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246). Journal of Clinical Investigation, 129(8), 3464. https://doi.org/10.1172/JCI131245

Erratum: Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246). / Hegde, Meenakshi; Mukherjee, Malini; Grada, Zakaria et al.
In: Journal of Clinical Investigation, Vol. 129, No. 8, 01.08.2019, p. 3464.

Research output: Contribution to journal › Comment/debate › peer-review

Hegde, M, Mukherjee, M, Grada, Z, Pignata, A, Landi, D, Navai, SA, Wakefield, A, Fousek, K, Bielamowicz, K, Chow, KKH, Brawley, VS, Byrd, TT, Krebs, S, Gottschalk, S, Wels, WS, Baker, ML, Dotti, G, Mamonkin, M, Brenner, MK, Orange, JS & Ahmed, N 2019, 'Erratum: Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246)', Journal of Clinical Investigation, vol. 129, no. 8, pp. 3464. https://doi.org/10.1172/JCI131245

Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai SA et al. Erratum: Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246). Journal of Clinical Investigation. 2019 Aug 1;129(8):3464. doi: 10.1172/JCI131245

Hegde, Meenakshi ; Mukherjee, Malini ; Grada, Zakaria et al. / Erratum : Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246). In: Journal of Clinical Investigation. 2019 ; Vol. 129, No. 8. pp. 3464.

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title = "Erratum: Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246)",

abstract = "A reader recently alerted the Journal that two images in this JCI article appear similar to images subsequently published in a Neuro-Oncology paper from the same lab as unique samples (1). Specifically, in Figure 9D of the JCI paper, the image for IL13Rα2 staining for the HER2 CAR sample appears to be similar to the image for EphA2 staining of a nontransduced T cell–treated sample published in Figure 6A of the Neuro-Oncology paper. In addition, in Figure 9D of the JCI paper, the image for IL13Rα2 staining for the tumor sample appears to be similar to the image for HER2 staining of a nontransduced T cell–treated sample in Figure 6B of the Neuro-Oncology paper. An institutional investigation into this matter is ongoing, and we will inform our readers of the outcome when the investigation is complete.",

author = "Meenakshi Hegde and Malini Mukherjee and Zakaria Grada and Antonella Pignata and Daniel Landi and Navai, {Shoba A.} and Amanda Wakefield and Kristen Fousek and Kevin Bielamowicz and Chow, {Kevin K.H.} and Brawley, {Vita S.} and Byrd, {Tiara T.} and Simone Krebs and Stephen Gottschalk and Wels, {Winfried S.} and Baker, {Matthew L.} and Gianpietro Dotti and Maksim Mamonkin and Brenner, {Malcolm K.} and Orange, {Jordan S.} and Nabil Ahmed",

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AU - Hegde, Meenakshi

AU - Mukherjee, Malini

AU - Grada, Zakaria

AU - Pignata, Antonella

AU - Landi, Daniel

AU - Navai, Shoba A.

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AU - Fousek, Kristen

AU - Bielamowicz, Kevin

AU - Chow, Kevin K.H.

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AU - Byrd, Tiara T.

AU - Krebs, Simone

AU - Gottschalk, Stephen

AU - Wels, Winfried S.

AU - Baker, Matthew L.

AU - Dotti, Gianpietro

AU - Mamonkin, Maksim

AU - Brenner, Malcolm K.

AU - Orange, Jordan S.

AU - Ahmed, Nabil

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N2 - A reader recently alerted the Journal that two images in this JCI article appear similar to images subsequently published in a Neuro-Oncology paper from the same lab as unique samples (1). Specifically, in Figure 9D of the JCI paper, the image for IL13Rα2 staining for the HER2 CAR sample appears to be similar to the image for EphA2 staining of a nontransduced T cell–treated sample published in Figure 6A of the Neuro-Oncology paper. In addition, in Figure 9D of the JCI paper, the image for IL13Rα2 staining for the tumor sample appears to be similar to the image for HER2 staining of a nontransduced T cell–treated sample in Figure 6B of the Neuro-Oncology paper. An institutional investigation into this matter is ongoing, and we will inform our readers of the outcome when the investigation is complete.

AB - A reader recently alerted the Journal that two images in this JCI article appear similar to images subsequently published in a Neuro-Oncology paper from the same lab as unique samples (1). Specifically, in Figure 9D of the JCI paper, the image for IL13Rα2 staining for the HER2 CAR sample appears to be similar to the image for EphA2 staining of a nontransduced T cell–treated sample published in Figure 6A of the Neuro-Oncology paper. In addition, in Figure 9D of the JCI paper, the image for IL13Rα2 staining for the tumor sample appears to be similar to the image for HER2 staining of a nontransduced T cell–treated sample in Figure 6B of the Neuro-Oncology paper. An institutional investigation into this matter is ongoing, and we will inform our readers of the outcome when the investigation is complete.

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Erratum: Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma (Journal of Clinical Investigation (2019) 129:8 (3464) DOI:10.1172/JCI131246)

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