TY - JOUR
T1 - Factors and outcomes associated with surgical treatment options of contralateral breast cancer
AU - Arrington, Amanda K.
AU - Voci, Amy
AU - Reparaz, Laura
AU - Fry, William
N1 - Publisher Copyright:
© 2014 Elsevier Inc.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Methods: The Surveillance, Epidemiology, and End Results (SEER) cancer database was queried to identify CBC patients from 1998 to 2010.Results: Of 1,534 patients, 31% underwent lumpectomy and 69% underwent mastectomy [201 (21%) mastectomy/reconstruction; 748 (69%) mastectomy alone]. Older patients (age >80 years) were more likely to undergo lumpectomy; those with larger tumors (T4) or node-positive disease more often underwent mastectomy. Overall survival was significantly higher in the mastectomy/reconstruction group (P =.05)Conclusions: Younger age, larger tumor size, and positive nodal disease were independently associated with mastectomy. As the number of long-term breast cancer survivors increases, factors contributing to CBC treatments must be studied to maximize survival potential.Background The treatment for a contralateral breast cancer (CBC) presents a growing dilemma given the expanding number of long-term survivors.
AB - Methods: The Surveillance, Epidemiology, and End Results (SEER) cancer database was queried to identify CBC patients from 1998 to 2010.Results: Of 1,534 patients, 31% underwent lumpectomy and 69% underwent mastectomy [201 (21%) mastectomy/reconstruction; 748 (69%) mastectomy alone]. Older patients (age >80 years) were more likely to undergo lumpectomy; those with larger tumors (T4) or node-positive disease more often underwent mastectomy. Overall survival was significantly higher in the mastectomy/reconstruction group (P =.05)Conclusions: Younger age, larger tumor size, and positive nodal disease were independently associated with mastectomy. As the number of long-term breast cancer survivors increases, factors contributing to CBC treatments must be studied to maximize survival potential.Background The treatment for a contralateral breast cancer (CBC) presents a growing dilemma given the expanding number of long-term survivors.
KW - Contralateral breast
KW - Second breast cancer
KW - Surgical treatments
KW - cancer
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U2 - 10.1016/j.amjsurg.2014.05.010
DO - 10.1016/j.amjsurg.2014.05.010
M3 - Article
C2 - 25129430
AN - SCOPUS:84908221762
SN - 0002-9610
VL - 208
SP - 524
EP - 530
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 4
ER -