Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease

Richard K. Burt; Malcolm Brenner; William Burns; Eva Courier; Gary Firestein; Bevra Hahn; Helen Heslop; Charles Link; Henry McFarland; Martin Roland; Mary Territo; George Tsokos; Ann Traynor

doi:10.1023/A:1006673408343

Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease

Richard K. Burt, Malcolm Brenner, William Burns, Eva Courier, Gary Firestein, Bevra Hahn, Helen Heslop, Charles Link, Henry McFarland, Martin Roland, Mary Territo, George Tsokos, Ann Traynor

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

In phase I (safety) trials, we have demonstrated the feasibility of autologous hematopoietic stem cell transplantation (HSCT) for patients with autoimmune diseases. Although this review comments on results of our phase I trials, the focus is on phase II (efficacy) trials using gene-marked autologous stem cells.

Original language	English (US)
Pages (from-to)	1-9
Number of pages	9
Journal	Journal of Clinical Immunology
Volume	20
Issue number	1
DOIs	https://doi.org/10.1023/A:1006673408343
State	Published - 2000

Keywords

Autoimmune disease
Gene-marked autologous stem cells
Hematopoietic stem cell transplantation

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1023/A:1006673408343

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keywords = "Autoimmune disease, Gene-marked autologous stem cells, Hematopoietic stem cell transplantation",

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AU - Burt, Richard K.

AU - Brenner, Malcolm

AU - Burns, William

AU - Courier, Eva

AU - Firestein, Gary

AU - Hahn, Bevra

AU - Heslop, Helen

AU - Link, Charles

AU - McFarland, Henry

AU - Roland, Martin

AU - Territo, Mary

AU - Tsokos, George

AU - Traynor, Ann

PY - 2000

Y1 - 2000

N2 - In phase I (safety) trials, we have demonstrated the feasibility of autologous hematopoietic stem cell transplantation (HSCT) for patients with autoimmune diseases. Although this review comments on results of our phase I trials, the focus is on phase II (efficacy) trials using gene-marked autologous stem cells.

AB - In phase I (safety) trials, we have demonstrated the feasibility of autologous hematopoietic stem cell transplantation (HSCT) for patients with autoimmune diseases. Although this review comments on results of our phase I trials, the focus is on phase II (efficacy) trials using gene-marked autologous stem cells.

KW - Autoimmune disease

KW - Gene-marked autologous stem cells

KW - Hematopoietic stem cell transplantation

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Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease

Abstract

Keywords

ASJC Scopus subject areas

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