Genetic engineering of T-cell receptors: TCR takes to titin

Helen E. Heslop

doi:10.1182/blood-2013-06-509604

Genetic engineering of T-cell receptors: TCR takes to titin

Helen E. Heslop

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

In this issue of Blood, Linette et al report a cautionary tale - a lethal off-target toxicity following T-cell receptor (TCR) optimization to enhance affinity against a tumor-associated antigen, MAGE-A3.

Original language	English (US)
Pages (from-to)	853-854
Number of pages	2
Journal	Blood
Volume	122
Issue number	6
DOIs	https://doi.org/10.1182/blood-2013-06-509604
State	Published - Aug 8 2013

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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10.1182/blood-2013-06-509604

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title = "Genetic engineering of T-cell receptors: TCR takes to titin",

abstract = "In this issue of Blood, Linette et al report a cautionary tale - a lethal off-target toxicity following T-cell receptor (TCR) optimization to enhance affinity against a tumor-associated antigen, MAGE-A3.",

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year = "2013",

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doi = "10.1182/blood-2013-06-509604",

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JO - Blood

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Genetic engineering of T-cell receptors: TCR takes to titin

Abstract

ASJC Scopus subject areas

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