TY - JOUR
T1 - Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens
T2 - a systematic analysis for the Global Burden of Disease Study 2016
AU - GBD 2016 Occupational Risk Factors Collaborators
AU - Driscoll, Tim
AU - Rushton, Lesley
AU - Hutchings, Sally J.
AU - Straif, Kurt
AU - Steenland, Kyle
AU - Abate, Degu
AU - Abbafati, Cristiana
AU - Acharya, Dilaram
AU - Adebayo, Oladimeji M.
AU - Afshari, Mahdi
AU - Akinyemiju, Tomi
AU - Alahdab, Fares
AU - Anjomshoa, Mina
AU - Antonio, Carl Abelardo T.
AU - Aremu, Olatunde
AU - Ataro, Zerihun
AU - Quintanilla, Beatriz Paulina Ayala
AU - Banoub, Joseph Adel Mattar
AU - Barker-Collo, Suzanne Lyn
AU - Bärnighausen, Till Winfried
AU - Barrero, Lope H.
AU - Bedi, Neeraj
AU - Behzadifar, Masoud
AU - Behzadifar, Meysam
AU - Benavides, Fernando G.
AU - Beuran, Mircea
AU - Bhattacharyya, Krittika
AU - Bijani, Ali
AU - Cárdenas, Rosario
AU - Carrero, Juan J.
AU - Carvalho, Félix
AU - Castañeda-Orjuela, Carlos A.
AU - Cerin, Ester
AU - Cooper, Cyrus
AU - Dandona, Lalit
AU - Dandona, Rakhi
AU - Dang, Anh Kim
AU - Daryani, Ahmad
AU - Desalegn, Beruk Berhanu
AU - Dharmaratne, Samath Dhamminda
AU - Dubljanin, Eleonora
AU - El-Khatib, Ziad
AU - Eskandarieh, Sharareh
AU - Fareed, Mohammad
AU - Faro, Andre
AU - Fereshtehnejad, Seyed Mohammad
AU - Fernandes, Eduarda
AU - Filip, Irina
AU - Fischer, Florian
AU - Fukumoto, Takeshi
N1 - Publisher Copyright:
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.
PY - 2020/3/1
Y1 - 2020/3/1
N2 - Objectives: This study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study. Methods: The GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors. Results: In 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39-1.68) million deaths and 76.1 (66.3-86.3) million DALYs were attributable to the included occupational risk factors, accounting for 2.8% of deaths and 3.2% of DALYs from all causes. Most deaths were attributable to PMGF, carcinogens (particularly asbestos), injury risk factors and SHS. Most DALYs were attributable to injury risk factors and ergonomic exposures. Men and persons 55 years or older were most affected. PAFs ranged from 26.8% for low back pain from ergonomic risk factors and 19.6% for hearing loss from noise to 3.4% for carcinogens. DALYs per capita were highest in Oceania, Southeast Asia and Central sub-S aharan Africa. On a per capita basis, between 1990 and 2016 there was an overall decrease of about 31% in deaths and 25% in DALYs. Conclusions: Occupational exposures continue to cause an important health burden worldwide, justifying the need for ongoing prevention and control initiatives.
AB - Objectives: This study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study. Methods: The GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors. Results: In 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39-1.68) million deaths and 76.1 (66.3-86.3) million DALYs were attributable to the included occupational risk factors, accounting for 2.8% of deaths and 3.2% of DALYs from all causes. Most deaths were attributable to PMGF, carcinogens (particularly asbestos), injury risk factors and SHS. Most DALYs were attributable to injury risk factors and ergonomic exposures. Men and persons 55 years or older were most affected. PAFs ranged from 26.8% for low back pain from ergonomic risk factors and 19.6% for hearing loss from noise to 3.4% for carcinogens. DALYs per capita were highest in Oceania, Southeast Asia and Central sub-S aharan Africa. On a per capita basis, between 1990 and 2016 there was an overall decrease of about 31% in deaths and 25% in DALYs. Conclusions: Occupational exposures continue to cause an important health burden worldwide, justifying the need for ongoing prevention and control initiatives.
KW - asbestos
KW - diesel engine exhaust
KW - epidemiology
KW - occupational exposure
KW - silica
UR - http://www.scopus.com/inward/record.url?scp=85079339823&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85079339823&partnerID=8YFLogxK
U2 - 10.1136/oemed-2019-106012
DO - 10.1136/oemed-2019-106012
M3 - Review article
C2 - 32054819
AN - SCOPUS:85079339823
SN - 1351-0711
VL - 77
SP - 151
EP - 159
JO - Occupational and Environmental Medicine
JF - Occupational and Environmental Medicine
IS - 3
ER -