TY - JOUR
T1 - Global, regional, and national incidence of six major immune-mediated inflammatory diseases
T2 - findings from the global burden of disease study 2019
AU - GBD 2019 IMID Collaborators
AU - Wu, Dongze
AU - Jin, Yingzhao
AU - Xing, Yuhan
AU - Abate, Melsew Dagne
AU - Abbasian, Mohammadreza
AU - Abbasi-Kangevari, Mohsen
AU - Abbasi-Kangevari, Zeinab
AU - Abd-Allah, Foad
AU - Abdelmasseh, Michael
AU - Abdollahifar, Mohammad Amin
AU - Abdulah, Deldar Morad
AU - Abedi, Aidin
AU - Abedi, Vida
AU - Abidi, Hassan
AU - Aboagye, Richard Gyan
AU - Abolhassani, Hassan
AU - Abuabara, Katrina
AU - Abyadeh, Morteza
AU - Addo, Isaac Yeboah
AU - Adeniji, Kayode Nelson
AU - Adepoju, Abiola Victor
AU - Adesina, Miracle Ayomikun
AU - Sakilah Adnani, Qorinah Estiningtyas
AU - Afarideh, Mohsen
AU - Aghamiri, Shahin
AU - Agodi, Antonella
AU - Agrawal, Anurag
AU - Aguilera Arriagada, Constanza Elizabeth
AU - Ahmad, Aqeel
AU - Ahmad, Danish
AU - Ahmad, Sajjad
AU - Ahmad, Sohail
AU - Ahmadi, Ali
AU - Ahmed, Ali
AU - Ahmed, Ayman
AU - Aithala, Janardhana P.
AU - Ajadi, Abdullateef Abiodun
AU - Ajami, Marjan
AU - Akbarzadeh-Khiavi, Mostafa
AU - Alahdab, Fares
AU - AlBataineh, Mohammad T.
AU - Alemi, Sharifullah
AU - Saeed Al-Gheethi, Adel Ali
AU - Ali, Liaqat
AU - Alif, Sheikh Mohammad
AU - Almazan, Joseph Uy
AU - Almustanyir, Sami
AU - Alqahtani, Jaber S.
AU - Alqasmi, Ibrahim
AU - Khan Altaf, Ihsan Ullah
N1 - Funding Information:
DZ Wu acknowledges support from Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (2022QN38). A Ahmad acknowledges support from Shaqra University . A N Bhat acknowledges support from Kasturba Medical College, Mangalore, Manipal Academy of Higher Education. V B Bitra acknowledges support from the School of Pharmacy, University of Botswana. K Bora acknowledges support from the Indian Council of Medical Research (ICMR) under the research scheme titled ‘ICMR Capacity Building for Disease Estimation and Projection’ for the area Non-communicable Diseases. R Buchbinder is supported by an Australian National Health and Medical Research Council (NHMRC) Investigator Fellowship. G Damiani acknowledges support from the Italian Center of Precision Medicine and Chronic Inflammation in Milan. A Fatehizadeh acknowledges support from the Department of Environmental Health Engineering of Isfahan University of Medical Sciences , Isfahan, Iran. V K Gupta acknowledges funding support from National Health and Medical Research Council (NHMRC), Australia. S Haque acknowledges support from Jazan University , Saudi Arabia for providing the access of Saudi Digital Library for this study. J Haubold acknowledges support from The Clinician Scientist Program of the Clinician Scientist Academy (UMEA) of the University Hospital Essen. N Ismail acknowledges support from AIMST University, Malaysia. N Joseph acknowledges the Department of Community Medicine , Kasturba Medical College, Mangalore , Manipal Academy of Higher Education, Manipal, India for their encouragement and support in this research work. H Kandel is supported by a Kornhauser Research Fellowship at The University of Sydney . J Lám acknowledges support from the National Research, Development and Innovation Office Hungary . K Latief acknowledges support from Taipei Medical University for Doctoral Education during the conduct of this review. G Liu was supported by CREATE Hope Scientific Fellowship from Lung Foundation Australia . A G Mathioudakis was supported by the National Institute for Health and Care Research Manchester Biomedical Research Centre and an NIHR Clinical Lectureship in Respiratory Medicine. J Padubidri acknowledges Kasturba Medical College, Mangalore and Manipal Academy of Higher Education, Manipal for their collaborative support for the research. A R Pathan acknowledges Author Gate Publications for their support. I Qattea acknowledges support from the Cleveland Clinic Foundation and Nassau University Medical center. A Raggi is supported by the Italian Ministry of Health (RRC). E M M Redwan acknowledges support from King Abdulaziz University (DSR), Jeddah, and King Abdulaziz City for Science & Technology (KACSAT), Saudi Arabia, Science & Technology Development Fund (STDF), and US-Egypt Science & Technology joint Fund : The Academy of Scientific Research and Technology ( ASRT ), Egypt. M Rodrigues was partially supported by the Centre of Studies in Geography and Spatial Planning. U Saeed would like to acknowledge the International Center of Medical Sciences Research (ICMSR), Islamabad Pakistan. A M Samy acknowledges the support from Ain Shams University and the Egyptian Fulbright Mission Program. A Schuermans was supported by the Belgian American Educational Foundation . A Sheikh acknowledges support from Health Data Research UK . R Tabarés-Seisdedos is supported by the Spanish Ministry of Science and Innovation , Institute of Health Carlos III , CIBERSAM , and INCLIVA . S Tabatabaei would like to acknowledge the Clinical Research Development Unit , Imam Reza Hospital, Mashhad University of Medical Sciences, for their assistance. M Tabish would like to acknowledge Shaqra University for supporting this work. M R Tovani-Palone acknowledges Saveetha Institute of Medical and Technical Sciences and SRM Institute of Science and Technology for supporting this study. Sai Ullah acknowledges support by University of Agriculture, Faisalabad-Pakistan. Y Xing acknowledges support from the Chinese University of Hong Kong Research Committee Postdoctoral Fellowship Scheme. G Yahya acknowledges the institutional support of the Department of Microbiology and Immunology , Faculty of Pharmacy , Zagazig University, Egypt . A Zumla acknowledges support from the European (EU) and Developing Countries Clinical Trials Partnership , the EU Horizon 2020 Framework Programme , UK-National Institute for Health and Care Research , the Mahathir Science Award Foundation and EU-EDCTP.
Publisher Copyright:
© 2023 The Author(s)
PY - 2023/10
Y1 - 2023/10
N2 - Background: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of −0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = −0.41), inflammatory bowel disease (AAPC = −0.72), multiple sclerosis (AAPC = −0.26), psoriasis (AAPC = −0.77), and atopic dermatitis (AAPC = −0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR. Interpretation: The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rheumatoid arthritis and upsurging new cases of other five IMIDs, respectively. Funding: The Global Burden of Disease Study is funded by the Bill and Melinda Gates Foundation. The project funded by Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital ( 2022QN38).
AB - Background: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of −0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = −0.41), inflammatory bowel disease (AAPC = −0.72), multiple sclerosis (AAPC = −0.26), psoriasis (AAPC = −0.77), and atopic dermatitis (AAPC = −0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR. Interpretation: The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rheumatoid arthritis and upsurging new cases of other five IMIDs, respectively. Funding: The Global Burden of Disease Study is funded by the Bill and Melinda Gates Foundation. The project funded by Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital ( 2022QN38).
KW - Global burden of disease study
KW - Immune-mediated inflammatory disease
KW - Incidence
KW - Trend
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U2 - 10.1016/j.eclinm.2023.102193
DO - 10.1016/j.eclinm.2023.102193
M3 - Article
C2 - 37731935
AN - SCOPUS:85172929794
SN - 2589-5370
VL - 64
SP - 102193
JO - EClinicalMedicine
JF - EClinicalMedicine
M1 - 102193
ER -